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Publication Date2014-05
A guide to genome engineering with programmable nucleases
Highly Cited Paper
Hyongbum Kim; Jin-Soo Kim
NATURE REVIEWS GENETICS, v.15, no.5, pp.321 - 334
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Publication Date2017-03
A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting
Kim, SJ; Omer Habib; Jin-Soo Kim, et al
STEM CELL RESEARCH, v.19, pp.52 - 54
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Publication Date2016-08
A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system
Hyeran Kim; Sang-Tae Kim; Jahee Ryu, et al
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, v.58, no.8, pp.705 - 712
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Publication Date2019-10
A zero-background CRISPR binary vector system for construction of sgRNA libraries in plant functional genomics applications
Jae‑Young Yun; Sang‑Tae Kim; Kim S.-G., et al
PLANT BIOTECHNOLOGY REPORTS, v.13, no.5, pp.543 - 551
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Publication Date2018-06
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
Highly Cited Paper
Seuk-Min Ryu; Taeyoung Koo; Kyoungmi Kim, et al
NATURE BIOTECHNOLOGY, v.36, no.6, pp.536 - 539
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Publication Date2021-11
Adenine base editor engineering reduces editing of bystander cytosines
Jeong, You Kyeong; Lee, SeokHoon; Hwang, Gue-Ho, et al
NATURE BIOTECHNOLOGY, v.39, no.11, pp.1426 - 1433
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Publication Date2021-02
Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities
Lyu, Pin; Lu, Zuyan; Sung-Ik Cho, et al
CRISPR JOURNAL, v.4, no.1, pp.69 - 81
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Publication Date2019-10
Adenine base editors catalyze cytosine conversions in human cells
Heon Seok Kim; Jeong Y.K.; Hur J.K., et al
NATURE BIOTECHNOLOGY, v.37, no.10, pp.1145 - 1148
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Publication Date2017-12
Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis
Jin-Dan Kang; Hyojin Kim; Long Jin, et al
ONCOTARGET, v.8, no.70, pp.115480 - 115489
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Publication Date2018-06
Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection
Heon Seok Kim; Kyungjin Lee; Seong-Jun Kim, et al
GENOME RESEARCH, v.28, no.6, pp.859 - 868
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Publication Date2022-07
Base editing in human cells with monomeric DddA-TALE fusion deaminases
Young Gun Mok; Ji Min Lee; Eugene Chung, et al
Nature Communications, v.13, no.1
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Publication Date2021-04-08
Base Editing in Progeria
Jin‑Soo Kim; Eriksson, Maria
NEW ENGLAND JOURNAL OF MEDICINE, v.384, no.14, pp.1364 - 1366
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Publication Date2016-10
Bypassing GMO regulations with CRISPR gene editing
Jungeun Kim; Jin-Soo Kim
NATURE BIOTECHNOLOGY, v.34, no.10, pp.1014 - 1015
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Publication Date2017-01
Cas-Analyzer: an online tool for assessing genome editing results using NGS data
Highly Cited Paper
Jeongbin Park; Kayeong Lim; Jin-Soo Kim, et al
BIOINFORMATICS, v.33, no.2, pp.286 - 288
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Publication Date2016-07
Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9
Jeongbin Park; Jin-Soo Kim; Sangsu Bae
BIOINFORMATICS, v.32, no.13, pp.2017 - 2023
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Publication Date2015-12
Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites
Jeongbin Park; Sangsu Bae; Jin Soo Kim
BIOINFORMATICS, v.31, no.24, pp.4014 - 4016
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Publication Date2021-07
Chloroplast and mitochondrial DNA editing in plants
Highly Cited Paper
Beum-Chang Kang; Su-Ji Bae; Seonghyun Lee, et al
NATURE PLANTS, v.7, no.7, pp.899 - 905
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Publication Date2017-08
Correction of a pathogenic gene mutation in human embryos
Highly Cited Paper
Hong Ma; Nuria Marti-Gutierrez; Sang-Wook Park, et al
NATURE, v.548, no.7668, pp.413 - 419
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Publication Date2015-05
CRISPR germline engineering - The community speaks
Katrine S Bosley; Michael Botchan; Annelien Bredenoord, et al
NATURE BIOTECHNOLOGY, v.33, no.5, pp.478 - 486
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Publication Date2018-03
CRISPR RNAs trigger innate immune responses in human cells
Sojung Kim; Taeyoung Koo; Hyeon-Gun Jee, et al
GENOME RESEARCH, v.28, no.3, pp.367 - 373
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Publication Date2020-10
CRISPR-Cas12a with an oAd Induces Precise and Cancer-Specific Genomic Reprogramming of EGFR and Efficient Tumor Regression
Yoon, A.-R.; Jung, B.-K.; Choi, E., et al
MOLECULAR THERAPY, v.28, no.10, pp.2286 - 2296
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Publication Date2019-05
CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells
Marion Gruffaz; Hongfeng Yuan; Wen Meng, et al
MBIO, v.10, no.3, pp.e00866 - 19
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Publication Date2019-10
CRISPR-Cas9–mediated therapeutic editing of Rpe65 ameliorates the disease phenotypes in a mouse model of Leber congenital amaurosis
Jo D.H.; Song D.W.; Cho C.S., et al
SCIENCE ADVANCES, v.5, no.10, pp.eaax1210
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Publication Date2018-05
CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Taeyoung Koo; Sung Wook Park; Dong Hyun Jo, et al
NATURE COMMUNICATIONS, v.9, no.1, pp.1855
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Publication Date2019-08
CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors
Choongil Lee; Dong Hyun Jo; Gue-Ho Hwang, et al
MOLECULAR THERAPY, v.27, no.8, pp.1364 - 1371
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Publication Date2020-06
CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells
Gue-Ho Hwang; Jihyeon Yu; Soyeon Yang, et al
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, v.18, pp.1686 - 1694
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Publication Date2019-02
CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion
Viktorija Globyte; Seung Hwan Lee; Taegeun Bae, et al
EMBO JOURNAL, v.38, no.4, pp.e99466
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Publication Date2016-06
CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii
Sung-Eun Shin; Jong-Min Lim; Hyun Gi Koh, et al
SCIENTIFIC REPORTS, v.6, pp.27810
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Publication Date2020-01
CRISPR/Cas9-mediated editing of 1-aminocyclopropane-1-carboxylate oxidase1 enhances Petunia flower longevity
Xu J.; Beum-Chang Kang; Naing A.H., et al
PLANT BIOTECHNOLOGY JOURNAL, v.18, no.1, pp.287 - 297
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Publication Date2017-06
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection
Heon Seok Kim; Kyungjin Lee; Sangsu Bae, et al
JOURNAL OF BIOLOGICAL CHEMISTRY, v.292, no.25, pp.10664 - 10671
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Publication Date2017-02
CRISPR/Cpf1-mediated DNA-free plant genome editing
Highly Cited Paper
Hyeran Kim; Sang-Tae Kim; Jahee Ryu, et al
NATURE COMMUNICATIONS, v.8, pp.14406
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Publication Date2018-11
DCas9-mediated Nanoelectrokinetic Direct Detection of Target Gene for Liquid Biopsy
Hyomin Lee; Jihye Choi; Euihwan Jeong, et al
NANO LETTERS, v.18, no.12, pp.7642 - 7650
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Publication Date2018-12
DIG-seq: A genome-wide CRISPR off-target profiling method using chromatin DNA
Daesik Kim; Jin-Soo Kim
GENOME RESEARCH, v.28, no.12, pp.1894 - 1900
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Publication Date2017-06
Digenome-seq web tool for profiling CRISPR specificity
Jeongbin Park; Liam Childs; Daesik Kim, et al
NATURE METHODS, v.14, no.6, pp.548 - 549
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Publication Date2015-03
Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Highly Cited Paper
Daesik Kim; Sangsu Bae; Jeongbin Park, et al
NATURE METHODS, v.12, no.3, pp.237 - 243
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Publication Date2018-07
Direct observation of DNA target searching and cleavage by CRISPR-Cas12a
Yongmoon Jeon; You Hee Choi; Yunsu Jang, et al
NATURE COMMUNICATIONS, v.9, no.1, pp.2777
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Publication Date2018-08
Directed evolution of CRISPR-Cas9 to increase its specificity
Highly Cited Paper
Jungjoon K. Lee; Euihwan Jeong; Joonsun Lee, et al
NATURE COMMUNICATIONS, v.9, no.1, pp.3048
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Publication Date2016-12
DNA-free genetically edited grapevine and apple protoplast using CRISPR/Cas9 ribonucleoproteins
Highly Cited Paper
Mickael Malnoy; Robert Viola; Min-Hee Jung, et al
FRONTIERS IN PLANT SCIENCE, v.7, pp.1904
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Publication Date2015-11
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
Highly Cited Paper
Je Wook Woo; Jungeun Kim; Soon Il Kwon, et al
NATURE BIOTECHNOLOGY, v.33, no.11, pp.1162 - U156
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Publication Date2016-07
DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins
Kwangryul Baek; Duk Hyoung Kim; Jooyeon Jeong, et al
SCIENTIFIC REPORTS, v.6, pp.30620
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Publication Date2015-11
Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells
Jia Liu; Thomas Gaj; Yifeng Yang, et al
NATURE PROTOCOLS, v.10, no.11, pp.1842 - 1859
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Publication Date2015-07
Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells
WooJae Choi; Eunji Kim; Soo-Young Yum, et al
PRION, v.9, no.4, pp.278 - 291
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Publication Date2022-10
Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases
Seonghyun Lee; Lee, Hyunji; Ga Young Baek, et al
GENOME BIOLOGY, v.23, no.1
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Publication Date2014-08
Enrichment of cells with TALEN-induced mutations using surrogate reporters
Young-Hoon Kim; Suresh Ramakrishna; Hyongbum Kim, et al
METHODS, v.69, no.1, pp.108 - 117
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Publication Date2019-03
Evaluating and enhancing target specificity of gene-editing nucleases and deaminases
Daesik Kim; Luk K.; Wolfe S.A., et al
ANNUAL REVIEW OF BIOCHEMISTRY, v.88, pp.191 - 220
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Publication Date2023-01
Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches
Kwon, J.; Kim, M.; Hwang, W., et al
Genome Biology, v.24, no.1
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Publication Date2017-01
Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute
Seung Hwan Lee; Giandomenico Turchiano; Hirotaka Ata, et al
NATURE BIOTECHNOLOGY, v.35, no.1, pp.17 - 18
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Publication Date2019-08
FAOBMB Award for Research Excellence
김진수
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Publication Date2016-07
Fine-Tuning Next-Generation Genome Editing Tools
Chidananda Nagamangala Kanchiswamy; Massimo Maffei; Mickael Malnoy, et al
TRENDS IN BIOTECHNOLOGY, v.34, no.7, pp.562 - 574
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Publication Date2015-08
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9
Chul-Yong Park; Duk Hyoung Kim; Jeong Sang Son, et al
CELL STEM CELL, v.17, no.2, pp.213 - 220
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Publication Date2018-06
Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9
Taeyoung Koo; Ngoc B. Lu-Nguyen; Alberto Malerba, et al
MOLECULAR THERAPY, v.26, no.6, pp.1529 - 1538
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Publication Date2017-11
Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1
Kweon, J; Jang, AH; Da-eun Kim, et al
NATURE COMMUNICATIONS, v.8, pp.1723
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Publication Date2017-08
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia
Kyle J. Hewitt; Koichi R. Katsumura; Daniel R. Matson, et al
DEVELOPMENTAL CELL, v.42, no.3, pp.213 - 225.e4
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Publication Date2015-01
Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus
Hanh Witte; Eduatdo Moreno; Christian Rodelsperger, et al
DEVELOPMENT GENES AND EVOLUTION, v.255, no.1, pp.55 - 62
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Publication Date2022-03
Generation of a Dystrophin Mutant in Dog by Nuclear Transfer Using CRISPR/Cas9-Mediated Somatic Cells: A Preliminary Study
Oh, Hyun Ju; Eugene Chung; Kim, Jaehwan, et al
International Journal of Molecular Sciences, v.23, no.5
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Publication Date2017-03
Generation of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9
Kim, SJ; Omer Habib; Jin-Soo Kim, et al
STEM CELL RESEARCH, v.19, pp.46 - 48
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Publication Date2017-02
Generation of cloned adult muscular pigs with myostatin gene mutation by genetic engineering
Kang J.-D.; Kim S.; Zhu H.-Y., et al
RSC ADVANCES, v.7, no.21, pp.12541 - 12549
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Publication Date2019-10
Generation of early-flowering Chinese cabbage (Brassica rapa spp. pekinensis) through CRISPR/Cas9-mediated genome editing
So Young Jeong; Hyomin Ahn; Jahee Ryu, et al
PLANT BIOTECHNOLOGY REPORTS, v.13, no.5, pp.491 - 499
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Publication Date2019-12
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells
Yoshimura Y.; Yamanishi A.; Kamitani T., et al
PLOS ONE, v.14, no.12, pp.0225740
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Publication Date2016-09
Genome editing comes of age
Jin-Soo Kim
NATURE PROTOCOLS, v.11, no.9, pp.1573 - 1578