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Cas-Analyzer: an online tool for assessing genome editing results using NGS dataHighly Cited Paper

Cited 95 time in webofscience Cited 99 time in scopus
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Title
Cas-Analyzer: an online tool for assessing genome editing results using NGS data
Author(s)
Jeongbin Park; Kayeong Lim; Jin-Soo Kim; Sangsu Bae
Publication Date
2017-01
Journal
BIOINFORMATICS, v.33, no.2, pp.286 - 288
Publisher
OXFORD UNIV PRESS
Abstract
Genome editing with programmable nucleases has been widely adopted in research and medicine. Next generation sequencing (NGS) platforms are now widely used for measuring the frequencies of mutations induced by CRISPR-Cas9 and other programmable nucleases. Here, we present an online tool, Cas-Analyzer, a JavaScript-based implementation for NGS data analysis. Because Cas-Analyzer is completely used at a client-side web browser on-the-fly, there is no need to upload very large NGS datasets to a server, a time-consuming step in genome editing analysis. Currently, Cas-Analyzer supports various programmable nucleases, including single nucleases and paired nucleases. (C) The Author 2016.
URI
https://pr.ibs.re.kr/handle/8788114/3364
DOI
10.1093/bioinformatics/btw561
ISSN
1367-4803
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
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