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C-H bond arylation of anilides inside copper-exchanged zeolites
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JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, v.417, pp.64 - 70
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Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism
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Scientific Reports, v.11, no.1
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Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia
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Genes & Genomics, v.45, no.2, pp.157 - 167
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Comparison of 3-month cytogenetic and molecular assays for early assessment of long-term clinical impact after BCR-ABL1 tyrosine kinase inhibitor treatment in chronic myeloid leukemia
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Leukemia Research, v.112
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Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs
Bredeson, Jessen V.; Mudd, Austin B.; Medina-Ruiz, Sofia, et al
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Publication Date2023-12
Convergent differentiation of multiciliated cells
Chae, Shinhyeok; Tae Joo Park; Taejoon Kwon
Scientific Reports, v.13, no.1
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Publication Date2016-12
Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex
Jeong H.; Park J.; Changwook Lee
EMBO REPORTS, v.17, no.12, pp.1857 - 1871
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Crystal structures of Mmm1 and Mdm12-Mmm1 reveal mechanistic insight into phospholipid trafficking at ER-mitochondria contact sites
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.114, no.45, pp.E9502 - E9511
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Deciphering Molecular Mechanism of Histone Assembly by DNA Curtain Technique
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Journal of Visualized Experiments, v.2022, no.181
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Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins
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International Journal of Molecular Sciences, v.24, no.22
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Direct diversification of unmasked quinazolin-4(3H)-ones through orthogonal reactivity modulation
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CHEMICAL COMMUNICATIONS, v.53, no.75, pp.10394 - 10397
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Distinct Motifs in ATAD5 C-Terminal Domain Modulate PCNA Unloading Process
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DNA polymerase theta-mediated repair of high LET radiation-induced complex DNA double-strand breaks
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Editorial for the Special Issue “Molecular Mechanism of Leukemia”
An, Jungeun; Myunggon Ko
International Journal of Molecular Sciences, v.24, no.18
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Efficient copper catalysts for C[sbnd]H bond arylation under microwave heating: Direct access to multi-substituted pivanilides
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Publication Date2023-11
Enrichment of Deleterious Mutated Genes Involved in Ciliary Function and Histone Modification in Brain Cancer Patient-Derived Xenograft Models
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Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation
An, Jungeun; Myunggon Ko
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.24, no.2
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Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy
Jung, Inkyung; An, Jungeun; Myunggon Ko
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Eukaryotic DNA replication: Orchestrated action of multi-subunit protein complexes
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Evolution of protein-coupled RNA dynamics during hierarchical assembly of ribosomal complexes
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NATURE COMMUNICATIONS, v.8, no.1, pp.492
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Ewing sarcoma protein promotes dissociation of poly(ADP-ribose) polymerase 1 from chromatin
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Experimental systems for the analysis of mutational signatures: no 'one-size-fits-all' solution
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Extracellular matrixes and neuroinflammation
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Extracorporeal Blood Treatment Using Functional Magnetic Nanoclusters Mitigates Organ Dysfunction of Sepsis in Swine
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Small Methods, v.8, no.5
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FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response
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Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca2+ homeostasis
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GCA links TRAF6-ULK1-dependent autophagy activation in resistant chronic myeloid leukemia
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GJA1 depletion causes ciliary defects by affecting Rab11 trafficking to the ciliary base
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ELIFE, v.11
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High-throughput single-molecule imaging system using nanofabricated trenches and fluorescent DNA-binding proteins
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Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia
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American Journal of Human Genetics, v.104, no.3, pp.439 - 453
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Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch
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Proceedings of the National Academy of Sciences of the United States of America, v.120, no.6
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Integrin beta-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge
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Genes & Genomics, v.44, no.4, pp.405 - 413
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ITGBL1 modulates integrin activity to promote cartilage formation and protect against arthritis
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SCIENCE TRANSLATIONAL MEDICINE, v.10, no.462, pp.7486
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Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression
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Proceedings of the National Academy of Sciences of the United States of America, v.119, no.26
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Mebendazole preferentially inhibits cilia formation and exerts anticancer activity by synergistically augmenting DNA damage
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Biomedicine & Pharmacotherapy, v.174
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Publication Date2019-08
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.116, no.35, pp.17438 - 17443
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Molecular characteristics of reiterative DNA unwinding by the Caenorhabditis elegans RecQ helicase
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NUCLEIC ACIDS RESEARCH, v.47, no.18, pp.9708 - 9720
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Publication Date2023-06
MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1
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PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity
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PCNA Unloading Is Negatively Regulated by BET Proteins
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Precision targeting tumor cells using cancer-specific InDel mutations with CRISPR-Cas9
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Proceedings of the National Academy of Sciences of the United States of America, v.119, no.9
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Publication Date2019
President Award
김남우
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Publication Date2022-07
PWWP2B promotes DNA end resection and homologous recombination
Ju, Min Kyung; Lee, Joo Rak; Choi, Yeonsong, et al
EMBO Reports, v.23, no.7
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Publication Date2024-04
RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
Son, Mi Young; Belan, Ondrej; Spirek, Mario, et al
iScience, v.27, no.4
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Publication Date2022-11
Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia
Park, Kibeom; Yoo, Hee-Seop; Chang-Kyu Oh, et al
Cancer Medicine, v.11, no.212, pp.4005 - 4020
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Publication Date2022-11
Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1
Chung, Scisung; Mi-Sun Kang; Alimbetov, Dauren S., et al
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2019-06
Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes
Mi-Sun Kang; Eunjin Ryu; Seung-Won Lee, et al
NATURE COMMUNICATIONS, v.10, pp.2420
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Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration
Son, Boram; Kim, Minju; Won, Hyosub, et al
Journal of Nanobiotechnology, v.21, no.1
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Sequence-dependent DNA condensation as a driving force of DNA phase separation
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Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination
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SHPRH as a new player in ribosomal RNA transcription and its potential role in homeostasis of ribosomal DNA repeats
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Simple Method to Characterize the Ciliary Proteome of Multiciliated Cells
Sim H.J.; Yun S.; Kim H.E., et al
JOURNAL OF PROTEOME RESEARCH, v.19, no.1, pp.391 - 400
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Single-molecule fluorescence imaging techniques reveal molecular mechanisms underlying deoxyribonucleic acid damage repair
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FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, v.10
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Single-Molecule Imaging Reveals the Mechanism Underlying Histone Loading of Schizosaccharomyces pombe AAA+ ATPase Abo1
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Molecules and cells, v.44, no.2, pp.79 - 87
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Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B
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NUCLEIC ACIDS RESEARCH, v.47, no.16, pp.8337 - 8347
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ssDNA reeling is an intermediate step in the reiterative DNA unwinding activity of the WRN-1 helicase
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Journal of Biological Chemistry, v.299, no.9
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Studying R-Loop Recognizing Proteins Using Single-Molecule DNA Curtain Technique and Electrophoretic Mobility Shift Assay
Cheon, Na Young; Ja Yil Lee
Methods in molecular biology (Clifton, N.J.), v.2528, pp.253 - 269
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Subtyping of influenza A H1N1 virus using a label-free electrochemical biosensor based on the DNA aptamer targeting the stem region of HA protein
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TET family dioxygenases and DNA demethylation in stem cells and cancers
Jungeun An; Anjana Rao; Myunggon Ko
EXPERIMENTAL AND MOLECULAR MEDICINE, v.49, no.4, pp.e323
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The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation
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NUCLEIC ACIDS RESEARCH, v.48, no.5, pp.2604 - 2620