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Publication Date2024-05
A comprehensive analysis integrating phenotypic assessment uncovering thornless cultivar lineages in Aralia elata
Kim, Jaewook; Park, Yunmi; Moon, Suyun, et al
Genomics, v.116, no.3
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Publication Date2016-08
A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system
Hyeran Kim; Sang-Tae Kim; Jahee Ryu, et al
JOURNAL OF INTEGRATIVE PLANT BIOLOGY, v.58, no.8, pp.705 - 712
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Publication Date2023-08
A streamlined guide RNA screening system for genome editing in Sorghum bicolor
Jeong Sun Lee; Su-Ji Bae; Kim, Jin-Soo, et al
Plant Methods, v.19, no.1
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Publication Date2018-06
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy
Highly Cited Paper
Seuk-Min Ryu; Taeyoung Koo; Kyoungmi Kim, et al
NATURE BIOTECHNOLOGY, v.36, no.6, pp.536 - 539
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Publication Date2021-02
Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities
Lyu, Pin; Lu, Zuyan; Sung-Ik Cho, et al
CRISPR JOURNAL, v.4, no.1, pp.69 - 81
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Publication Date2019-10
Adenine base editors catalyze cytosine conversions in human cells
Heon Seok Kim; Jeong Y.K.; Hur J.K., et al
NATURE BIOTECHNOLOGY, v.37, no.10, pp.1145 - 1148
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Publication Date2017-12
Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis
Jin-Dan Kang; Hyojin Kim; Long Jin, et al
ONCOTARGET, v.8, no.70, pp.115480 - 115489
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Publication Date2018-06
Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection
Heon Seok Kim; Kyungjin Lee; Seong-Jun Kim, et al
GENOME RESEARCH, v.28, no.6, pp.859 - 868
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Publication Date2022-07
Base editing in human cells with monomeric DddA-TALE fusion deaminases
Young Gun Mok; Ji Min Lee; Eugene Chung, et al
Nature Communications, v.13, no.1
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Publication Date2023-10
BLZ8 activates a plastidial peroxiredoxin and a ferredoxin to protect Chlamydomonas reinhardtii against oxidative stress
Choi, B.Y.; Park, H.; Kim, J., et al
Plant Biology, v.25, no.6, pp.915 - 923
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Publication Date2017-01
Cas-Analyzer: an online tool for assessing genome editing results using NGS data
Highly Cited Paper
Jeongbin Park; Kayeong Lim; Jin-Soo Kim, et al
BIOINFORMATICS, v.33, no.2, pp.286 - 288
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Publication Date2021-07
Chloroplast and mitochondrial DNA editing in plants
Highly Cited Paper
Beum-Chang Kang; Su-Ji Bae; Seonghyun Lee, et al
NATURE PLANTS, v.7, no.7, pp.899 - 905
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Publication Date2023-08
Comparative transcriptome analysis on wild-simulated ginseng of different age revealed possible mechanism of ginsenoside accumulation
Kim, Jaewook; Yun, Yeongbae; Huh, Jeonghoon, et al
Plant Physiology and Biochemistry, v.201
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Publication Date2018-03
CRISPR RNAs trigger innate immune responses in human cells
Sojung Kim; Taeyoung Koo; Hyeon-Gun Jee, et al
GENOME RESEARCH, v.28, no.3, pp.367 - 373
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Publication Date2018-05
CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Taeyoung Koo; Sung Wook Park; Dong Hyun Jo, et al
NATURE COMMUNICATIONS, v.9, no.1, pp.1855
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Publication Date2019-08
CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors
Choongil Lee; Dong Hyun Jo; Gue-Ho Hwang, et al
MOLECULAR THERAPY, v.27, no.8, pp.1364 - 1371
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Publication Date2018-06
CRISPR/Cas-based customization of pooled CRISPR libraries
Kweon, J; Da-eun Kim; Jang, AH, et al
PLOS ONE, v.13, no.6, pp.e0199473
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Publication Date2019-02
CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion
Viktorija Globyte; Seung Hwan Lee; Taegeun Bae, et al
EMBO JOURNAL, v.38, no.4, pp.e99466
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Publication Date2016-06
CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii
Sung-Eun Shin; Jong-Min Lim; Hyun Gi Koh, et al
SCIENTIFIC REPORTS, v.6, pp.27810
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Publication Date2017-06
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection
Heon Seok Kim; Kyungjin Lee; Sangsu Bae, et al
JOURNAL OF BIOLOGICAL CHEMISTRY, v.292, no.25, pp.10664 - 10671
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Publication Date2018-11
CRISPR/dCas9-mediated biosensor for detection of tick-borne diseases
Koo B.; Da-eun Kim; Kweon J., et al
SENSORS AND ACTUATORS B-CHEMICAL, v.273, pp.316 - 321
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Publication Date2017-12
CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR
Seung Hwan Lee; Jiyoung Yu; Gue Ho Hwang, et al
ONCOGENE, v.36, no.49, pp.6823 - 6829
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Publication Date2018-11
DCas9-mediated Nanoelectrokinetic Direct Detection of Target Gene for Liquid Biopsy
Hyomin Lee; Jihye Choi; Euihwan Jeong, et al
NANO LETTERS, v.18, no.12, pp.7642 - 7650
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Publication Date2017-06
Digenome-seq web tool for profiling CRISPR specificity
Jeongbin Park; Liam Childs; Daesik Kim, et al
NATURE METHODS, v.14, no.6, pp.548 - 549
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Publication Date2015-03
Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
Highly Cited Paper
Daesik Kim; Sangsu Bae; Jeongbin Park, et al
NATURE METHODS, v.12, no.3, pp.237 - 243
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Publication Date2018-08
Directed evolution of CRISPR-Cas9 to increase its specificity
Highly Cited Paper
Jungjoon K. Lee; Euihwan Jeong; Joonsun Lee, et al
NATURE COMMUNICATIONS, v.9, no.1, pp.3048
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Publication Date2015-11
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
Highly Cited Paper
Je Wook Woo; Jungeun Kim; Soon Il Kwon, et al
NATURE BIOTECHNOLOGY, v.33, no.11, pp.1162 - U156
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Publication Date2024-08
Draft genome sequence of bacterium Bacillus proteolyticus strain IMGN4 from soil
Yeongjun Kim; Sangmin Lee; Kim, Eunjeong, et al
Microbiology Resource Announcements, v.13, no.8
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Publication Date2015-07
Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells
WooJae Choi; Eunji Kim; Soo-Young Yum, et al
PRION, v.9, no.4, pp.278 - 291
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Publication Date2024-01
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA
Sung-Ik Cho; Kayeong Lim; Hong, Seongho, et al
Cell, v.187, no.1, pp.95 - 109.e26
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Publication Date2023-07
Exploiting Bacterial Genera as Biocontrol Agents: Mechanisms, Interactions and Applications in Sustainable Agriculture
Jaeyeon Lee; Soomin Kim; Hoseong Jung, et al
JOURNAL OF PLANT BIOLOGY, v.66
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Publication Date2017-08
Fabrication of photochromic hydrogels using an interpenetrating chitosan network
Lee, CW; Seung Hwan Lee; Yang, YK, et al
JOURNAL OF APPLIED POLYMER SCIENCE, v.134, no.30, pp.45120
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Publication Date2015-08
Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9
Chul-Yong Park; Duk Hyoung Kim; Jeong Sang Son, et al
CELL STEM CELL, v.17, no.2, pp.213 - 220
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Publication Date2018-06
Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9
Taeyoung Koo; Ngoc B. Lu-Nguyen; Alberto Malerba, et al
MOLECULAR THERAPY, v.26, no.6, pp.1529 - 1538
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Publication Date2017-11
Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1
Kweon, J; Jang, AH; Da-eun Kim, et al
NATURE COMMUNICATIONS, v.8, pp.1723
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Publication Date2022-03
Generation of a Dystrophin Mutant in Dog by Nuclear Transfer Using CRISPR/Cas9-Mediated Somatic Cells: A Preliminary Study
Oh, Hyun Ju; Eugene Chung; Kim, Jaehwan, et al
International Journal of Molecular Sciences, v.23, no.5
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Publication Date2017-03
Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration
Kyoungmi Kim; Sung Wook Park; Jin Hyoung Kim, et al
GENOME RESEARCH, v.27, no.3, pp.419 - 426
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Publication Date2016-08
Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells
Highly Cited Paper
Daesik Kim; Jungeun Kim; Junho K Hur, et al
NATURE BIOTECHNOLOGY, v.34, no.8, pp.863 - 868
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Publication Date2020-08
Genome-wide specificity of dCpf1 cytidine base editors
Daesik Kim; Kayeong Lim; Da-eun Kim, et al
NATURE COMMUNICATIONS, v.11, no.1, pp.4072
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Publication Date2017-05
Genome-wide target specificities of CRISPR RNA-guided programmable deaminases
Daesik Kim; Kayeong Lim; Sang-Tae Kim, et al
NATURE BIOTECHNOLOGY, v.35, no.5, pp.475 - 480
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Publication Date2016-03
Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
Daesik Kim; Sojung Kim; Sunghyun Kim, et al
GENOME RESEARCH, v.26, no.3, pp.406 - 415
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Publication Date2019-04
Genome-wide target specificity of CRISPR RNA-guided adenine base editors
Dae Sik Kim; Da-eun Kim; Gyeorae Lee, et al
NATURE BIOTECHNOLOGY, v.37, no.4, pp.430 - 435
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Publication Date2015-07
Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome
Kyle J. Hewitt; Duk Hyoung Kim; Prithvia Devadas, et al
MOLECULAR CELL, v.59, no.1, pp.62 - 74
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Publication Date2017-05
Highly efficient RNA-guided base editing in mouse embryos
Highly Cited Paper
Kyoungmi Kim; Seuk-Min Ryu; Sang-Tae Kim, et al
NATURE BIOTECHNOLOGY, v.35, no.5, pp.435 - 437
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Publication Date2014-06
Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
Highly Cited Paper
Sojung Kim; Daesik Kim; Seung Woo Cho, et al
GENOME RESEARCH, v.24, no.6, pp.1012 - 1019
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Publication Date2017-02
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
Highly Cited Paper
Eunji Kim; Taeyoung Koo; Sung Wook Park, et al
NATURE COMMUNICATIONS, v.8, pp.14500
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Publication Date2023-06
Intestinal Organoid as a Research Platform for the Virus-host Interaction
Lee, Jieun; Lee, Subin; Jeon, Hyungjun, et al
Journal of Bacteriology and Virology, v.53, no.1, pp.51 - 60
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Publication Date2018-12
Machine learning finds Cas9-edited genotypes
Sangsu Bae; Jin-Soo Kim
NATURE BIOMEDICAL ENGINEERING, v.2, no.12, pp.892 - 893
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Publication Date2014-07
Microhomology-based choice of Cas9 nuclease target sites
Sangsu Bae; Jiyeon Kweon; Heon Seok Kim, et al
NATURE METHODS, v.11, no.7, pp.705 - 706
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Publication Date2021-02-19
Mitochondrial DNA editing in mice with DddA-TALE fusion deaminases
Hyunji Lee; Seonghyun Lee; Gayoung Baek, et al
NATURE COMMUNICATIONS, v.12, no.1
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Publication Date2017-08
Myofibroblast in the ligamentum flavum hypertrophic activity
Junseok W. Hur; Taegeun Bae; Sunghyeok Ye, et al
EUROPEAN SPINE JOURNAL, v.26, no.8, pp.2021 - 2030
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Publication Date2022-01
Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases
Kayeong Lim; Sung-Ik Cho; Jin-Soo Kim
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2021-06
Off-the-Shelf, Immune-Compatible Human Embryonic Stem Cells Generated Via CRISPR-Mediated Genome Editing
Annie Kim; Kun-Gu Lee; Yeongbeen Kwon, et al
STEM CELL REVIEWS AND REPORTS, v.17, no.3, pp.1053 - 1067
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Publication Date2023-11
Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction
Jumee Kim; Kim, Somi; Lee, Seung-Yeon, et al
Science advances, v.9, no.47
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Publication Date2023-03
Prime editing with genuine Cas9 nickases minimizes unwanted indels
Jaesuk Lee; Kayeong Lim; Annie Kim, et al
Nature Communications, v.14, no.1
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Publication Date2022-05
Rationally designed nanoparticle delivery of Cas9 ribonucleoprotein for effective gene editing
Chae, Se-Youl; Euihwan Jeong; Kang, Seounghun, et al
Journal of Controlled Release, v.345, pp.108 - 119
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Publication Date2020-05
Recent advances in genome editing of stem cells for drug discovery and therapeutic application
Jaesuk Lee; Delger Bayarsaikhan; Govigerel Bayarsaikhan, et al
PHARMACOLOGY & THERAPEUTICS, v.209, pp.107501
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Publication Date2024-06
Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice
Wu, Szu-Hsien Sam; Kim, Somi; Heetak Lee, et al
Nature Communications, v.15, no.1
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Publication Date2017-11
Rescue of high-specificity Cas9 variants using sgRNAs with matched 5 ' nucleotides
Sojung Kim; Taegeun Bae; Jaewoong Hwang, et al
GENOME BIOLOGY, v.18, no.1, pp.218
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Publication Date2023-08
RNF43 and ZNRF3 in Wnt Signaling-A Master Regulator at the Membrane
Farnhammer, Fiona; Colozza, Gabriele; Jihoon Kim
INTERNATIONAL JOURNAL OF STEM CELLS, v.16