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Publication Date2023-09
GABA tone regulation and its cognitive functions in the brain
Wuhyun Koh; Kwak, Hankyul; Cheong, Eunji, et al
Nature Reviews Neuroscience, v.24, no.9, pp.523 - 539
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Publication Date2022-06
Generation of Astrocyte-Specific MAOB Conditional Knockout Mouse with Minimal Tonic GABA Inhibition
Jung Moo Lee; Moonsun Sa; Heeyoung An, et al
Experimental Neurobiology, v.31, no.3, pp.158 - 172
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Publication Date2022-10
Glutamate Permeability of Chicken Best1
Jung Moo Lee; Gadhe, Changdev Gorakshnath; Hyunji Kang, et al
Experimental Neurobiology, v.31, no.5, pp.277 - 288
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Publication Date2021-01-01
High-yield synthesis and purification of recombinant human GABA transaminase for high-throughput screening assays
Mingu Gordon Park; Ah-reum Han; Su Yeon Kim, et al
Journal of Enzyme Inhibition and Medicinal Chemistry, v.36, no.1, pp.2016 - 2024
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Publication Date2023-08
Hypothalamic GABRA5-positive neurons control obesity via astrocytic GABA
Moonsun Sa; Yoo, Eun-Seon; Wuhyun Koh, et al
Nature Metabolism, v.5, no.9, pp.1506 - 1525
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Publication Date2022-08
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis
Woojin Won; Choi, Hyun-Ji; Yoo, Ji-Young, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.54, no.8, pp.1188 - 1200
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Publication Date2022-02
Inhibition of monoamine oxidase B prevents reactive astrogliosis and scar formation in stab wound injury model
Heejung Chun; Jiwoon Lim; Park, Ki Duk, et al
GLIA, v.70, no.2, pp.354 - 367
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Publication Date2020-12
Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors
Dong Ho Woo; Young-Na Hur; Minwoo Wendy Jang, et al
ANIMAL CELLS AND SYSTEMS, v.24, no.6, pp.341 - 348
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Publication Date2021-10
KDS2010, a Newly Developed Reversible MAO-B Inhibitor, as an Effective Therapeutic Candidate for Parkinson’s Disease
Nam, Min-Ho; Park, Jong-Hyun; Song, Hyo Jung, et al
Neurotherapeutics, v.18, no.3, pp.1729 - 1747
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Publication Date2024-04
KDS2010, a reversible MAO-B inhibitor, extends the lifetime of neural probes by preventing glial scar formation
Chae, Uikyu; Chun, Heejung; Jiwoon Lim, et al
GLIA, v.72, no.4, pp.748 - 758
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Publication Date2023-06
Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice
Hyoseon Oh; Suho Lee; Oh, Yusang, et al
Nature Communications, v.14, no.1, pp.3547
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Publication Date2022-12
Lancemaside A from Codonopsis lanceolata: Studies on Antiviral Activity and Mechanism of Action against SARS-CoV-2 and Its Variants of Concern
Tai Young Kim; Jeon, Sangeun; Ko, Meehyun, et al
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, v.66, no.12
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Publication Date2024-01
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
Mridula Bhalla; C. Justin Lee
Molecular Brain, v.17, no.1
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Publication Date2022-05
Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation
Lee, Jingu; Kim, Joon-Goon; Hong, Sujung, et al
GLIA, v.70, no.5, pp.975 - 988
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Publication Date2022-12
MAO-B Inhibitor, KDS2010, Alleviates Spinal Nerve Ligation-induced Neuropathic Pain in Rats Through Competitively Blocking the BDNF/TrkB/NR2B Signaling
Phạm, Thuỳ Linh; Noh, Chan; Neupane, Chiranjivi, et al
Journal of Pain, v.23, no.12, pp.2092 - 2109
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Publication Date2023-12
Mapping Astrocytic and Neuronal μ-opioid Receptor Expression in Various Brain Regions Using MOR-mCherry Reporter Mouse
Woojin Won; Daeun Kim; Eunjin Shin, et al
Experimental Neurobiology, v.32, no.6, pp.395 - 409
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Publication Date2023-02
Negative Influence of the Hunger State on Rule-observance Behavior in Mice
Abdelrahman M. Alkahwaji; Hee Sup Shin; C. Justin Lee
Experimental Neurobiology, v.32, no.1, pp.31 - 41
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Publication Date2019-12
Neurovascular coupling under chronic stress is modified by altered GABAergic interneuron activity
Kayoung Han; Jiwoong Min; Myunghee Lee, et al
JOURNAL OF NEUROSCIENCE, v.39, no.50, pp.10081 - 10095
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Publication Date2019-03
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease
Park J.-H.; Ju Y.H.; Choi J.W., et al
SCIENCE ADVANCES, v.5, no.3, pp.eaav0316
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Publication Date2020-06
Optimization of primer sets and detection protocols for SARS-CoV-2 of coronavirus disease 2019 (COVID-19) using PCR and real-time PCR
Myungsun Park; Joungha Won; Byung Yoon Choi, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.52, no.6, pp.963 - 977
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Publication Date2022-02
Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior
Joungha Won; Yuriy Pankratov; Minwoo Wendy Jang, et al
Neuron, v.110, no.3, pp.423 - 435
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Publication Date2019-02
Pharmacological Dissection of Intrinsic Optical Signal Reveals a Functional Coupling between Synaptic Activity and Astrocytic Volume Transient
Woo, J; Han, YE; Wuhyun Koh, et al
EXPERIMENTAL NEUROBIOLOGY, v.28, no.1, pp.30 - 42
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Publication Date2021-05
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion
Tai Young Kim; Jeon, Sangeun; Jang, Youngho, et al
Experimental and Molecular Medicine, v.53, no.5, pp.956 - 972
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Publication Date2020-06
PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates
Choi J.-W.; Yeon Ha Ju; Choi Y., et al
ACS CHEMICAL NEUROSCIENCE, v.11, no.12, pp.1801 - 1810
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Publication Date2014-08
Rebound burst firing in the reticular thalamus is not essential for pharmacological absence seizures in mice
Seung Eun Lee; Jaekwang Lee; Charles Latchoumane, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.111, no.32, pp.11828 - 11833
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Publication Date2021-07
Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis
Cho, Hyun-U; Sunpil Kim; Sim, Jeongeun, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.53, no.7, pp.1148 - 1158
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Publication Date2021-11-27
Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus
Jea Kwon; Minwoo Wendy Jang; C. Justin Lee
Molecular Brain, v.14, no.1
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Publication Date2022-04
Revisiting the Role of Astrocytic MAOB in Parkinson's Disease
Nam, Min-Ho; Moonsun Sa; Yeon Ha Ju, et al
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.8
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Publication Date2022-02
Role of Hypothalamic Reactive Astrocytes in Diet-Induced Obesity
Moonsun Sa; Mingu Gordon Park; C. Justin Lee
Molecules and cells, v.45, no.2, pp.65 - 75
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Publication Date2020-04
Serial optical coherence microscopy for label-free volumetric histopathology
Min E.; Ban S.; Lee J., et al
SCIENTIFIC REPORTS, v.10, no.1, pp.6711
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Publication Date2020-11
Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2-production
Heejung Chun; Im, Hyeonjoo; Kang, You Jung, et al
NATURE NEUROSCIENCE, v.23, pp.1555 - 1566
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Publication Date2021-01
Signaling mechanisms of μ-opioid receptor (MOR) in the hippocampus: disinhibition versus astrocytic glutamate regulation
Min‑Ho Nam; Woojin Won; Kyung‑Seok Han, et al
CELLULAR AND MOLECULAR LIFE SCIENCES, v.78, no.2, pp.415 - 426
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Publication Date2020-04
Sleep-enhancing effects of phytoncide via behavioral, electrophysiological, and molecular modeling approaches
Junsung Woo; ChangJoon Justin Lee
EXPERIMENTAL NEUROBIOLOGY, v.29, no.2, pp.120 - 129
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Publication Date2022-10
Synthesis and structure–activity relationship study of saponin-based membrane fusion inhibitors against SARS-CoV-2
Jang, Youngho; Tai Young Kim; Jeon, Sangeun, et al
Bioorganic Chemistry, v.127
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Publication Date2016-12
The Ca2+ -activated chloride channel anoctamin-2 mediates spike-frequency adaptation and regulates sensory transmission in thalamocortical neurons
Go Eun Ha; Jaekwang Lee; Hankyul Kwak, et al
NATURE COMMUNICATIONS, v.7, pp.13791
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Publication Date2020-10
The molecular mechanism of synaptic activity-induced astrocytic volume transient
Junsung Woo; MinwooWendy Jang; Jaekwang Lee, et al
JOURNAL OF PHYSIOLOGY-LONDON, v.598, no.20, pp.4555 - 4572
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Publication Date2021-04
The pathological role of astrocytic MAOB in parkinsonism revealed by genetic ablation and over-expression of MAOB
Heeyoung An; Heo, Jun Young; C. Justin Lee, et al
Experimental Neurobiology, v.30, no.2, pp.113 - 119
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Publication Date2021-11-01
The tripartite glutamatergic synapse
Lalo, Ulyana; Wuhyun Koh; C. Justin Lee, et al
Neuropharmacology, v.199
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Publication Date2022-05
Trifluoperazine and Its Analog Suppressed the Tumorigenicity of Non-Small Cell Lung Cancer Cell; Applicability of Antipsychotic Drugs to Lung Cancer Treatment
Jeong, Joo Yeon; Park, Haangik; Yoo, Hong, et al
BIOMEDICINES, v.10, no.5
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Publication Date2021-04
Tumor spheroids of an aggressive form of central neurocytoma have transit-amplifying progenitor characteristics with enhanced EGFR and tumor stem cell signaling
Shin, Hye Young; Kyung-Seok Han; Park, Hyung Woo, et al
Experimental Neurobiology, v.30, no.2, pp.120 - 143
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Publication Date2019-04
Tweety-homolog (Ttyh) Family Encodes the Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel (VRAC(swell)) in the Brain
Young-Eun Han; Jea Kwon; Joungha Won, et al
EXPERIMENTAL NEUROBIOLOGY, v.28, no.2, pp.183 - 215
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Publication Date2021-02
Ultimate COVID-19 Detection Protocol Based on Saliva Sampling and qRT-PCR with Risk Probability Assessment
Joungha Won; Kazan, Hasan Huseyin; Jea Kwon, et al
EXPERIMENTAL NEUROBIOLOGY, v.30, no.1, pp.13 - 31
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Publication Date2019-10
Ultrasonic Neuromodulation via Astrocytic TRPA1
Soo-Jin Oh; Jung Moo Lee; Hyun-Bum Kim, et al
CURRENT BIOLOGY, v.29, no.20, pp.3386 - +
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Publication Date2022-06
Unaltered Tonic Inhibition in the Arcuate Nucleus of Diet-induced Obese Mice
Moonsun Sa; Jung Moo Lee; Mingu Gordon Park, et al
Experimental Neurobiology, v.31, no.3, pp.147 - 157
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Publication Date2023-07
Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using C-11-acetate and F-18-FDG
Nam, Min-Ho; Ko, Hae Young; Kim, Dongwoo, et al
BRAIN, v.146, no.7, pp.2957 - 2974
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Publication Date2023-02
Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant
Min, Kwang Wook; Kim, Namsuk; Lee, Jae Hoon, et al
EXPERIMENTAL AND MOLECULAR MEDICINE, v.55, no.2, pp.385 - 400
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Publication Date2022-10
Visuosocial Preference Memory, but Not Avoidance Memory, Requires PLCγ1 in the CA2 Hippocampus
Sunpil Kim; Kim, Jeongyeon; Yongmin Mason Park, et al
Experimental Neurobiology, v.31, no.5, pp.332 - 342
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Publication Date2018-10
Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse
Jong-Hyun Kim; Gireesh Gangadharan; Junweon Byun, et al
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.115, no.43, pp.11078 - 11083
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Publication Date2020-12
생명과학부분 연구성과 (연구자가 선정한 2020 국내 바이오분야 연구성과 TOP5)
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