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Publication Date2023-03
Limitations of gene editing assessments in human preimplantation embryos
Liang, Dan; Mikhalchenko, Aleksei; Ma, Hong, et al
Nature Communications, v.14, no.1
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Publication Date2023-03
Prime editing with genuine Cas9 nickases minimizes unwanted indels
Jaesuk Lee; Kayeong Lim; Annie Kim, et al
Nature Communications, v.14, no.1
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Publication Date2023-03
Precision mitochondrial DNA editing with high-fidelity DddA-derived base editors
Seonghyun Lee; Hyunji Lee; Ga Young Baek, et al
NATURE BIOTECHNOLOGY, v.41, no.3, pp.378 - 186
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Publication Date2023-01
Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches
Kwon, J.; Kim, M.; Hwang, W., et al
Genome Biology, v.24, no.1
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Publication Date2022-12
Targeted A-to-G base editing of chloroplast DNA in plants
Young Gun Mok; Sung Hyun Hong; Su Ji Bae, et al
Nature Plants, v.8, no.12, pp.1378 - 1384
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Publication Date2022-10
Enhanced mitochondrial DNA editing in mice using nuclear-exported TALE-linked deaminases and nucleases
Seonghyun Lee; Lee, Hyunji; Ga Young Baek, et al
GENOME BIOLOGY, v.23, no.1
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Publication Date2022-10
Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia
Ottaviano, Giorgio; Georgiadis, Christos; Gkazi, Soragia Athina, et al
Science Translational Medicine, v.14, no.668
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Publication Date2022-07
Base editing in human cells with monomeric DddA-TALE fusion deaminases
Young Gun Mok; Ji Min Lee; Eugene Chung, et al
Nature Communications, v.13, no.1
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Publication Date2022-07
Production of MSTN-mutated cattle without exogenous gene integration using CRISPR-Cas9
Gim, Gyeong-Min; Kwon, Dong-Hyeok; Eom, Kyeong-Hyun, et al
BIOTECHNOLOGY JOURNAL, v.17, no.7
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Publication Date2022-06
Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice
Whisenant, Daniel; Kayeong Lim; Revechon, Gwladys, et al
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2022-05
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases
Highly Cited Paper
Sung-Ik Cho; Seonghyun Lee; Young Geun Mok, et al
Cell, v.185, no.10, pp.1764 - 1776.e12
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Publication Date2022-05
Rationally designed nanoparticle delivery of Cas9 ribonucleoprotein for effective gene editing
Chae, Se-Youl; Euihwan Jeong; Kang, Seounghun, et al
Journal of Controlled Release, v.345, pp.108 - 119
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Publication Date2022-03
Generation of a Dystrophin Mutant in Dog by Nuclear Transfer Using CRISPR/Cas9-Mediated Somatic Cells: A Preliminary Study
Oh, Hyun Ju; Eugene Chung; Kim, Jaehwan, et al
International Journal of Molecular Sciences, v.23, no.5
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Publication Date2022-01
ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
Lam, Terence Y.W.; Nguyen, Ngan; Peh, Hong Yong, et al
Proceedings of the National Academy of Sciences of the United States of America, v.119, no.4
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Publication Date2022-01
Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases
Kayeong Lim; Sung-Ik Cho; Jin-Soo Kim
NATURE COMMUNICATIONS, v.13, no.1
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Publication Date2021-12
Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library
Naoki Miyamoto; Go, Young-Hyun; Larissa Miasiro Ciaramicoli, et al
RSC Chemical Biology, v.2, no.6, pp.1590 - 1593
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Publication Date2021-11
Adenine base editor engineering reduces editing of bystander cytosines
Jeong, You Kyeong; Lee, SeokHoon; Hwang, Gue-Ho, et al
NATURE BIOTECHNOLOGY, v.39, no.11, pp.1426 - 1433
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Publication Date2021-11
The functional association of acqos/victr with salt stress resistance in arabidopsis thaliana was confirmed by crispr-mediated mutagenesis
Kim, Sang-Tae; Minkyung Choi; Su-Ji Bae, et al
International Journal of Molecular Sciences, v.22, no.21
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Publication Date2021-07-02
PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
Hwang, Gue-Ho; Jeong, You Kyeong; Habib, Omer, et al
NUCLEIC ACIDS RESEARCH, v.49, no.W1, pp.W499 - W504
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Publication Date2021-07
Chloroplast and mitochondrial DNA editing in plants
Highly Cited Paper
Beum-Chang Kang; Su-Ji Bae; Seonghyun Lee, et al
NATURE PLANTS, v.7, no.7, pp.899 - 905