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Gain Switching for a Detection System to Accommodate a Newly Developed MALDI-Based Quantification Method

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Title
Gain Switching for a Detection System to Accommodate a Newly Developed MALDI-Based Quantification Method
Author(s)
Sung Hee Ahn; Taeghwan Hyeon; Myung Soo Kim; Jeong Hee Moon
Publication Date
2017-09
Journal
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, v.28, no.9, pp.1987 - 1990
Publisher
SPRINGER
Abstract
In matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF), matrix-derived ions are routinely deflected away to avoid problems with ion detection. This, however, limits the use of a quantification method that utilizes the analyte-to-matrix ion abundance ratio. In this work, we will show that it is possible to measure this ratio by a minor instrumental modification of a simple form of MALDI-TOF. This involves detector gain switching. [Figure not available: see fulltext.]. © 2017, American Society for Mass Spectrometry
URI
https://pr.ibs.re.kr/handle/8788114/4162
ISSN
1044-0305
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
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