BROWSE

Related Scientist

Researcher

나노입자 연구단
나노입자 연구단
more info

Tandem synthesis of amides and secondary amines from esters with primary amines under solvent-free conditions

Cited 15 time in webofscience Cited 0 time in scopus
289 Viewed 59 Downloaded
Title
Tandem synthesis of amides and secondary amines from esters with primary amines under solvent-free conditions
Author(s)
Jeongbin Lee; Muthaiah S.; Soon Hyeok Hong
Publication Date
2014-08
Journal
ADVANCED SYNTHESIS & CATALYSIS, v.356, no.11-12, pp.2653 - 2660
Publisher
WILEY-V C H VERLAG GMBH
Abstract
An iridium(III)-catalyzed tandem synthesis of amides and amines from esters under solvent-free conditions is described. A commercially available iridium(III) complex, [Cp*IrCl2]2, with sodium acetate showed the best activity for the synthesis of amides and secondary amines. The amide was formed by ester-amide exchange which generates an alcohol in situ which is subsequently transformed to a secondary amine via hydrogen autotransfer. This synthetic protocol with high atom economy generates water as the sole by-product and can afford amides and amines from various esters in a one-pot reaction, expanding the synthetic versatility of ester transformations. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
URI
https://pr.ibs.re.kr/handle/8788114/961
ISSN
1615-4150
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
Files in This Item:
Tandem synthesis of amides and secondary amines from esters with primary amines under solvent-free conditions.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse