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복잡계 자기조립 연구단
복잡계 자기조립 연구단
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Point-of-Use Detection of Amphetamine-Type Stimulants with Host-Molecule-Functionalized Organic Transistors

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Title
Point-of-Use Detection of Amphetamine-Type Stimulants with Host-Molecule-Functionalized Organic Transistors
Author(s)
Yoonjung Jang; Moonjeong Jang; Hyoeun Kim; Sang Jin Lee; Eunyeong Jin; Jin Young Koo; In-Chul Hwang; Yonghwi Kim; Young Ho Ko; Ilha Hwang; Joon Hak Oh; Kimoon Kim
Publication Date
2017-10
Journal
CHEM, v.3, no.4, pp.641 - 651
Publisher
Cell Press
Abstract
In recent years, there has been a rapid increase in the abuse of amphetaminetype stimulants (ATS). One way to tackle this problem is to develop an easy, sensitive, rapid, and cheap ATS detection platform. Here, a strategy that synergistically combines the selectivity of supramolecular chemistry and the sensitivity of organic field-effect transistors is used as the basis of an ATS sensor. Cucurbit[7]uril derivatives that can selectively detect ATS have been synthesized and used as a functional material. The fabricated amperometric sensors exhibited unprecedented sensitivity toward ATS, with a detection limit of nanomolar concentrations in urine and picomolar concentrations in water or a physiologic buffer. The feasibility of this strategy was further demonstrated through the preparation of flexible and wearable devices with a wireless sensing platform. This sensing system offers rapid and sensitive detection of trace amounts of ATS in urine and other samples at the point of use.2017 (c) 2017 Elsevier Inc.
URI
https://pr.ibs.re.kr/handle/8788114/4404
ISSN
2451-9294
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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