A high-density, high-channel count, multiplexed mu ECoG array for auditory-cortex recordings
Cited 41 time in
Cited 45 time in
1,469 Viewed
244 Downloaded
-
Title
- A high-density, high-channel count, multiplexed mu ECoG array for auditory-cortex recordings
-
Author(s)
- Escabi, MA; Read, HL; Viventi, J; Dae-Hyeong Kim; Higgins, NC; Storace, DA; Liu, ASK; Gifford, AM; Burke, JF; Campisi, M; Kim, YS; Avrin, AE; Van der Spiegel, J; Huang, YG; Li, M; Wu, J; Rogers, JA; Litt, B; Cohen, YE
-
Subject
- electrocorticography, ; ECoG, ; auditory cortex, ; topography, ; tonotopy
-
Publication Date
- 2014-09
-
Journal
- JOURNAL OF NEUROPHYSIOLOGY, v.112, no.6, pp.1566 - 1583
-
Publisher
- AMER PHYSIOLOGICAL SOC
-
Abstract
- Escabí MA, Read HL, Viventi J, Kim DH, Higgins NC, Storace
DA, Liu AS, Gifford AM, Burke JF, Campisi M, Kim YS, Avrin
AE, Van der Spiegel J, Huang Y, Li M, Wu J, Rogers JA, Litt B,
Cohen YE. A high-density, high-channel count, multiplexed ECoG
array for auditory-cortex recordings. J Neurophysiol 112: 1566–1583,
2014. First published June 11, 2014; doi:10.1152/jn.00179.2013.—
Our understanding of the large-scale population dynamics of neural
activity is limited, in part, by our inability to record simultaneously
from large regions of the cortex. Here, we validated the use of a
large-scale active microelectrode array that simultaneously records
196 multiplexed micro-electrocortigraphical (ECoG) signals from
the cortical surface at a very high density (1,600 electrodes/cm2). We
compared ECoG measurements in auditory cortex using a custom
“active” electrode array to those recorded using a conventional “passive”
ECoG array. Both of these array responses were also compared
with data recorded via intrinsic optical imaging, which is a standard
methodology for recording sound-evoked cortical activity. Custom
active ECoG arrays generated more veridical representations of the
tonotopic organization of the auditory cortex than current commercially
available passive ECoG arrays. Furthermore, the cortical
representation could be measured efficiently with the active arrays,
requiring as little as 13.5 s of neural data acquisition. Next, we
generated spectrotemporal receptive fields from the recorded neural
activity on the active ECoG array and identified functional organizational
principles comparable to those observed using intrinsic metabolic
imaging and single-neuron recordings. This new electrode
array technology has the potential for large-scale, temporally precise monitoring and mapping of the cortex, without the use of invasive
penetrating electrodes.
-
URI
- https://pr.ibs.re.kr/handle/8788114/922
-
DOI
- 10.1152/jn.00179.2013
-
ISSN
- 0022-3077
-
Appears in Collections:
- Center for Nanoparticle Research(나노입자 연구단) > 1. Journal Papers (저널논문)
- Files in This Item:
-
A high-density, high-channel count, multiplexed μECoG array for auditory-cortex recordings.pdfDownload
-
- Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.