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첨단연성물질 연구단
첨단연성물질 연구단
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A fidget spinner for the point-of-care diagnosis of urinary tract infection

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Title
A fidget spinner for the point-of-care diagnosis of urinary tract infection
Author(s)
Issac Michael; Dongyoung Kim; Oleksandra Gulenko; Sumit Kumar; Saravana Kumar; Jothi Clara; Dong Yeob Ki; Juhee Park; Hyun Yong Jeong; Taek Soo Kim; Sunghoon Kwon; Yoon-Kyoung Cho
Publication Date
2020-06
Journal
NATURE BIOMEDICAL ENGINEERING, v.4, no.6, pp.591 - 600
Publisher
NATURE PUBLISHING GROUP
Abstract
© 2020, The Author(s), under exclusive licence to Springer Nature Limited.The point-of-care detection of pathogens in biological samples in resource-limited settings should be inexpensive, rapid, portable, simple and accurate. Here, we describe a custom-made fidget spinner that rapidly concentrates pathogens in 1-ml samples of undiluted urine by more than 100-fold for the on-device colorimetric detection of bacterial load and pathogen identification. In Tiruchirappalli, India, the device enabled the on-site detection of infection with the naked eye within 50 min in urine samples from 39 patients suspected of having a urinary tract infection. We also show that, in 30 clinical samples of urinary tract infection, the device can be used to perform an antimicrobial susceptibility test for the antimicrobial drugs ciprofloxacin and cefazolin within 120 min. The fidget spinner could be used in low-resource settings as an inexpensive handheld point-of-care device for the rapid concentration and detection of pathogens in urine samples
URI
https://pr.ibs.re.kr/handle/8788114/7119
ISSN
2157-846X
Appears in Collections:
Center for Soft and Living Matter(첨단연성물질 연구단) > Journal Papers (저널논문)
Files in This Item:
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