BROWSE

Related Scientist

Researcher

유제중
복잡계 자기조립 연구단
more info

Hierarchical Self-Assembly of Poly-Pseudorotaxanes into Artificial Microtubules

Cited 0 time in webofscience Cited 0 time in scopus
12 Viewed 3 Downloaded
Title
Hierarchical Self-Assembly of Poly-Pseudorotaxanes into Artificial Microtubules
Author(s)
Hwang, W; Jejoong Yoo; In-Chul Hwang; Lee, J; Young Ho Ko; Hyun Woo Kim; Kim, Y; Lee, Y; Moon Young Hur; Kyeng Min Park; Seo, J; Kangkyun Baek; Kimoon Kim
Publication Date
2020-02
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.59, no.9, pp.3460 - 3464
Publisher
WILEY-V C H VERLAG GMBH
Abstract
Hierarchical self-assembly of building blocks over multiple length scales is ubiquitous in living organisms. Microtubules are one of the principal cellular components formed by hierarchical self-assembly of nanometer-sized tubulin heterodimers into protofilaments, which then associate to form micron-length-scale, multi-stranded tubes. This peculiar biological process is now mimicked with a fully synthetic molecule, which forms a 1:1 host-guest complex with cucurbit[7]uril as a globular building block, and then polymerizes into linear poly-pseudorotaxanes that associate laterally with each other in a self-shape-complementary manner to form a tubular structure with a length over tens of micrometers. Molecular dynamic simulations suggest that the tubular assembly consists of eight poly-pseudorotaxanes that wind together to form a 4.5 nm wide multi-stranded tubule. 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
URI
https://pr.ibs.re.kr/handle/8788114/7013
ISSN
1433-7851
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
Files in This Item:
Hwang_et_al-2020-Angewandte_Chemie_International_Edition.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse