BROWSE

Related Scientist

Researcher

나노입자 연구단
나노입자 연구단
more info

Large scale and integrated platform for digital mass culture of anchorage dependent cells

Cited 0 time in webofscience Cited 0 time in scopus
17 Viewed 3 Downloaded
Title
Large scale and integrated platform for digital mass culture of anchorage dependent cells
Author(s)
Kyoung Won Cho; Seok Joo Kim; Jaemin Kim; Song, SY; Wang Hee Lee; Wang, L; Min Soh; Lu, NS; Taeghwan Hyeon; Kim, BS; Dae-Hyeong Kim
Publication Date
2019-10
Journal
NATURE COMMUNICATIONS, v.10, no.1, pp.4824 -
Publisher
NATURE PUBLISHING GROUP
Abstract
© 2019, The Author(s).Industrial applications of anchorage-dependent cells require large-scale cell culture with multifunctional monitoring of culture conditions and control of cell behaviour. Here, we introduce a large-scale, integrated, and smart cell-culture platform (LISCCP) that facilitates digital mass culture of anchorage-dependent cells. LISCCP is devised through large-scale integration of ultrathin sensors and stimulator arrays in multiple layers. LISCCP provides real-time, 3D, and multimodal monitoring and localized control of the cultured cells, which thereby allows minimizing operation labour and maximizing cell culture performance. Wireless integration of multiple LISCCPs across multiple incubators further amplifies the culture scale and enables digital monitoring and local control of numerous culture layers, making the large-scale culture more efficient. Thus, LISCCP can transform conventional labour-intensive and high-cost cell cultures into efficient digital mass cell cultures. This platform could be useful for industrial applications of cell cultures such as in vitro toxicity testing of drugs and cosmetics and clinical scale production of cells for cell therapy
URI
https://pr.ibs.re.kr/handle/8788114/6841
ISSN
2041-1723
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
Files in This Item:
8.large scale.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse