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A thermoresponsive nanocarrier for mitochondria-targeted drug delivery

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Title
A thermoresponsive nanocarrier for mitochondria-targeted drug delivery
Author(s)
Wang D.; Huang H.; Zhou M.; Lu H.; Chen J.; Young-Tae Chang; Gao J.; Chai Z.; Hu Y.
Publication Date
2019-04
Journal
CHEMICAL COMMUNICATIONS, v.55, no.28, pp.4051 - 4054
Publisher
ROYAL SOC CHEMISTRY
Abstract
Mitochondria emerge as an important target for cancer therapy. Herein, by taking advantage of the recently reported high temperature of mitochondria, a well-tuned thermoresponsive nanocarrier was developed for specifically delivering the anticancer drug, paclitaxel (PTX), to mitochondria in cancer cells. The temperature-dependent delivery of drugs to mitochondria represents a novel anticancer strategy. © 2019 The Royal Society of Chemistry.
URI
https://pr.ibs.re.kr/handle/8788114/5872
ISSN
1359-7345
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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