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Dye-Cucurbit[n]uril complexes as sensor elements for reliable pattern recognition of biogenic polyamines

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Title
Dye-Cucurbit[n]uril complexes as sensor elements for reliable pattern recognition of biogenic polyamines
Author(s)
Kyeng Min Park; Kim J.; Young Ho Ko; Ahn Y.; James Murray; Meng Li; Annadka Shrinidhi; Kimoon Kim
Publication Date
2018-01
Journal
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, v.91, no.1, pp.95 - 99
Publisher
CHEMICAL SOC JAPAN
Abstract
The host-guest complexes between commercially available fluorescence dyes and cucurbit[n]urils (CB[n], n = 6, 7 and 8) were exploited as multiple sensor elements to provide arrays for sensing biogenic amines using principal component analysis (PCA). Since the sensor elements respond differently to each amine, the array generates distinct patterns of fluorescence changes for each amine. We analyzed these results using PCA to allow precise discrimination of individual biogenic amines. This result demonstrated the great potential of these host-guest complexes as useful sensor elements for biogenic molecules, which may be useful to develop a diagnostic tool for diseases including cancers. © 2018 The Chemical Society of Japan
URI
https://pr.ibs.re.kr/handle/8788114/4385
ISSN
0009-2673
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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