BROWSE

Related Scientist

Researcher

나노입자 연구단
나노입자 연구단
more info

Multifunctional nanoparticles as a tissue adhesive and an injectable marker for image-guided procedures

Cited 4 time in webofscience Cited 0 time in scopus
113 Viewed 31 Downloaded
Title
Multifunctional nanoparticles as a tissue adhesive and an injectable marker for image-guided procedures
Author(s)
Kwangsoo Shin; Choi J.W.; Giho Ko; Seungmin Baik; Dokyoon Kim; Ok Kyu Park; Lee K.; Cho H.R.; Sang Ihn Han; Soo Hong Lee; Dong Jun Lee; Lee N.; Kim H.-C.; Taeghwan Hyeon
Publication Date
2017-07
Journal
NATURE COMMUNICATIONS, v.8, no., pp.15807 -
Publisher
NATURE PUBLISHING GROUP
Abstract
Tissue adhesives have emerged as an alternative to sutures and staples for wound closure and reconnection of injured tissues after surgery or trauma. Owing to their convenience and effectiveness, these adhesives have received growing attention particularly in minimally invasive procedures. For safe and accurate applications, tissue adhesives should be detectable via clinical imaging modalities and be highly biocompatible for intracorporeal procedures. However, few adhesives meet all these requirements. Herein, we show that biocompatible tantalum oxide/silica core/shell nanoparticles (TSNs) exhibit not only high contrast effects for real-time imaging but also strong adhesive properties. Furthermore, the biocompatible TSNs cause much less cellular toxicity and less inflammation than a clinically used, imageable tissue adhesive (that is, a mixture of cyanoacrylate and Lipiodol). Because of their multifunctional imaging and adhesive property, the TSNs are successfully applied as a hemostatic adhesive for minimally invasive procedures and as an immobilized marker for image-guided procedures. © The Author(s) 2017
URI
http://pr.ibs.re.kr/handle/8788114/4242
DOI
10.1038/ncomms15807
ISSN
2041-1723
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
Files in This Item:
11.multifunctional nanoparticles as a tissue.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse