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Surface design of magnetic nanoparticles for stimuli-responsive cancer imaging and therapy Highly Cited Paper

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Title
Surface design of magnetic nanoparticles for stimuli-responsive cancer imaging and therapy
Author(s)
Taegyu Kang; Fangyuan Li; Seungmin Baik; Wei Shao; Daishun Ling; Taeghwan Hyeon
Publication Date
2017-08
Journal
BIOMATERIALS, v.136, no., pp.98 - 114
Publisher
ELSEVIER SCI LTD
Abstract
Magnetic nanoparticles (MNPs) have been extensively studied for their potential applications to cancer diagnosis and treatment. However, various obstacles limit the use of nanoparticles for delivery in the tumor microenvironment. As a viable solution to such obstacles, advances in nanoparticle surface engineering augmented by a profound understanding of cancer physiology present new opportunities for MNP-based imaging and therapeutic agents. Stimuli-responsive ligands, rationally designed to interact with various physicochemical aspects, can improve the performance of MNPs in cancer-targeted imaging and therapy. In this review, we highlight recent progress in the design of MNP-based stimuli-responsive nanomaterials and their applications to cancer diagnosis and treatment. © 2017 Elsevier Ltd.
URI
https://pr.ibs.re.kr/handle/8788114/4239
ISSN
0142-9612
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
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