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복잡계 자기조립 연구단
복잡계 자기조립 연구단
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Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages

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Title
Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages
Author(s)
Junghong Park; Swapan Pramanick; Jinhwan Kim; Jihyun Lee; Won Jong Kim
Publication Date
2017-10
Journal
CHEMICAL COMMUNICATIONS, v.53, no.81, pp.11229 - 11232
Publisher
ROYAL SOC CHEMISTRY
Abstract
In this study, we designed NO-activatable gold nanoparticles (NAM-AuNPs) for specific targeting and photo-thermal ablation of macrophages. The gold nanoparticles showed aggregation behavior in response to NO solution as well as endogenous NO secreted from activated macrophages. Following NIR irradiation, significant cytotoxicity was observed in activated RAW 264.7 cells treated with NAM-AuNPs. © 2017 The Royal Society of Chemistry
URI
https://pr.ibs.re.kr/handle/8788114/4105
ISSN
1359-7345
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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