BROWSE

Related Scientist

Researcher

나노입자 연구단
나노입자 연구단
more info

Bioresorbable Electronic Stent Integrated with Therapeutic Nanoparticles for Endovascular Diseases

Cited 41 time in webofscience Cited 0 time in scopus
151 Viewed 3 Downloaded
Title
Bioresorbable Electronic Stent Integrated with Therapeutic Nanoparticles for Endovascular Diseases
Author(s)
Donghee Son; Jongha Lee; Dong Jun Lee; Ghaffari R.; Yun S.; Seok Joo Kim; Ji Eun Lee; Hye Rim Cho; Yoon S.; Yang S.; Lee S.; Qiao S.; Ling D.; Sanghun Shin; Jun-Kyul Song; Jaemin Kim; Taeho Kim; Hakyong Lee; Jonghoon Kim; Min Soh; Lee N.; Hwang C.S.; Nam S.; Lu N.; Taeghwan Hyeon; Seung Hong Choi; Dae-Hyeong Kim
Publication Date
2015-06
Journal
ACS NANO, v.9, no.6, pp.5937 - 5946
Publisher
AMER CHEMICAL SOC
Abstract
Implantable endovascular devices such as bare metal, drug eluting, and bioresorbable stents have transformed interventional care by providing continuous structural and mechanical support to many peripheral, neural, and coronary arteries affected by blockage. Although effective in achieving immediate restoration of blood flow, the long-term re-endothelialization and inflammation induced by mechanical stents are difficult to diagnose or treat. Here we present nanomaterial designs and integration strategies for the bioresorbable electronic stent with drug-infused functionalized nanoparticles to enable flow sensing, temperature monitoring, data storage, wireless power/data transmission, inflammation suppression, localized drug delivery, and hyperthermia therapy. In vivo and ex vivo animal experiments as well as in vitro cell studies demonstrate the previously unrecognized potential for bioresorbable electronic implants coupled with bioinert therapeutic nanoparticles in the endovascular system. © 2015 American Chemical Society
URI
https://pr.ibs.re.kr/handle/8788114/2347
ISSN
1936-0851
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
Files in This Item:
9.acsnano(Bioresorbable Electronic).pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse