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IBS Publications RepositoryCenter for Self-assembly and Complexity(복잡계 자기조립 연구단)1. Journal Papers (저널논문)
Fluorescence switch for silver ion detection utilizing dimerization of DNA-Ag nanoclusters
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- Title
- Fluorescence switch for silver ion detection utilizing dimerization of DNA-Ag nanoclusters
- Author(s)
- Jihyun Lee; Juhee Park; Lee, HH; Park, H; Kim, HI; Won Jong Kim
- Subject
- DNA-template silver nanoclusters, Silver ion detection, Fluorescent probes, Fluorescence switch
- Publication Date
- 2015-01
- Journal
- BIOSENSORS & BIOELECTRONICS, v.68, no.68, pp.642 - 647
- Publisher
- ELSEVIER ADVANCED TECHNOLOGY
- Abstract
- A fluorescenceswitchthatconsistsofDNA-templatedsilvernanoclusters(DNA-AgNCs)triggeredby silverion(Agþ) isdevelopedtodetectAgþ. Themechanismofthe fluorescence switchingofDNA-AgNCs is investigatedby fluorescence spectroscopy,circulardichroismspectroscopy,DNAhybridizationassay and massspectrometry.Agþ induces adimericstructureofCyt12-AgNCsbyformingabridgebetween two Cyt12-AgNCs,whereCyt12 is cytosine12-mer;thisdimerformationcausesthe fluorescence change of Cyt12-AgNCs fromredtogreen.UsingthisAgþ-triggered fluorescenceswitch,wesuccessfullydetected Agþ at concentrationsaslowas10nM.Furthermore,wequantitativelydetectedtheAgþ in the Silmazins, whichisdermatologicalburnointmenthavingsilversulfadiazine.Agþ detection usingthis fluorescence switchhashighselectivityandsensitivity,andshortresponsetime,andcanbeusedsuc- cessfully eveninthepresenceofothermetalions.
- ISSN
- 0956-5663
- Appears in Collections:
- Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > 1. Journal Papers (저널논문)
- Files in This Item:
- 1-s2.0-S0956566315000755-main.pdfDownload
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