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나노입자 연구단
나노입자 연구단
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Electronic sensor and actuator webs for large-area complex geometry cardiac mapping and therapy

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Title
Electronic sensor and actuator webs for large-area complex geometry cardiac mapping and therapy
Author(s)
Dae-Hyeong Kim; Roozbeh Ghaffari; Nanshu Lu; Shuodao Wang; Stephen P. Lee; Hohyun Keum; Robert D’Angelo; Lauren Klinker; Yewang Su; Chaofeng Lu; Yun-Soung Kim; Abid Ameen; Yuhang Li; Yihui Zhang; Bassel de Graff; Yung-Yu Hsu; ZhuangJian Liu; Jeremy Ruskin; Lizhi Xu; Chi Lu; Fiorenzo G. Omenetto; Yonggang Huang; Moussa Mansour; Marvin J. Slepian; John A. Rogerse
Publication Date
2012-12
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.109, no.49, pp.19910 - 19915
Publisher
NATL ACAD SCIENCES
Abstract
Curved surfaces, complex geometries, and time-dynamic deformations of the heart create challenges in establishing intimate, nonconstraining interfaces between cardiac structures and medical devices or surgical tools, particularly over large areas.We constructed large area designs for diagnostic and therapeutic stretchable sensor and actuator webs that conformally wrap the epicardium, establishing robust contact without sutures, mechanical fixtures, tapes, or surgical adhesives. These multifunctional web devices exploit open, mesh layouts and mount on thin, bio-resorbable sheets of silk to facilitate handling in a way that yields, after dissolution, exceptionally low mechanical moduli and thicknesses. In vivo studies in rabbit and pig animal models demonstrate the effectiveness of these device webs for measuring and spatially mapping temperature, electrophysiological signals, strain, and physical contact in sheet and balloon-based systems that also have the potential to deliver energy to perform localized tissue ablation.
URI
https://pr.ibs.re.kr/handle/8788114/1417
ISSN
0027-8424
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > Journal Papers (저널논문)
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