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나노물질 및 화학반응 연구단
나노물질 및 화학반응 연구단
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A New Helicase Assay Based on Graphene Oxide for Anti-Viral Drug Development

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Title
A New Helicase Assay Based on Graphene Oxide for Anti-Viral Drug Development
Author(s)
Hongje Jang; Soo-Ryoon Ryoo; Min Jae Lee; Sang Woo Han; Dal-Hee Min
Publication Date
2013-04
Journal
MOLECULES AND CELLS, v.35, no.4, pp.269 - 273
Publisher
KOREAN SOC MOLECULAR & CELLULAR BIOLOGY
Abstract
Recently, graphene oxide (GO), one of the carbon nanomaterials, has received much attention due to its unique physical and chemical properties and high potential in many research areas, including applications as a biosensor and drug delivery vehicle. Various GO-based biosensors have been developed, largely based on its surface adsorption properties for detecting biomolecules, such as nucleotides and peptides, and real-time monitoring of enzymatic reactions. In this review, we discuss recent advances in GO-based biosensors focusing on a novel assay platform for helicase activity, which was also employed in high-throughput screening to discover selective helicase inhibitors.
URI
https://pr.ibs.re.kr/handle/8788114/1355
ISSN
1016-8478
Appears in Collections:
Center for Nanomaterials and Chemical Reactions(나노물질 및 화학반응 연구단) > Journal Papers (저널논문)
Center for RNA Research(RNA 연구단) > Journal Papers (저널논문)
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