IBS Publications Repository: Graphene oxide-based drug delivery vehicles: functionalization, characterization, and cytotoxicity evaluation

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Graphene oxide-based drug delivery vehicles: functionalization, characterization, and cytotoxicity evaluation

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Title: Graphene oxide-based drug delivery vehicles: functionalization, characterization, and cytotoxicity evaluation

Author(s): Sami Makharza; Giuseppe Cirillo; Alicja Bachmatiuk; Imad Ibrahim; Nicholas Ioannides; Barbara Trzebicka; Silke Hampel; Mark H.Rummeli

Subject: Graphene oxide, ; Nanocarrier, ; Drug therapy, ; Health effects, ; Nanomedicine

Abstract: As a consequence of graphene oxides (GOs) high chemical versatility, there is great interest in functionalized as a nanocarrier for in vitro and in vivo drug delivery. Within this review, the structure and properties of GO that allow covalent and noncovalent functionalization are discussed. In short, toxicity investigations show functionalized GO is biocompatible. Various works demonstrate the potential of GO derivatives as exciting nanocarriers for the loading and delivery of therapeutic drugs.