Understanding of how the nanostructure materials such as quantum dots, nanowires, nanotubes, and graphene are grown from self-assembly of atoms and molecules and their fascinating new nanophysics remain as one of the unconquered frontier sciences. The low dimensional materials can be easily hybridized to reveal multifunctional performance, which has never been realized in conventional approaches. Recent progress in ideal two-dimensional layered structures such as graphene, boron nitride, metal oxide, and their hybridization with zero- and/or one-dimensional nanostructures has opened new exciting research areas in tunneling phenomena, enhanced carrier mobility, charge injection/extraction spectroscopy, thermoelectric, and photonic crystals. Nevertheless, growth control of nanostructures and design of such hybrid structures are very challenging and often difficult task to attain intuition from physics point of view. Because of this difficulty, researches in nanostructure materials cannot be done in a small laboratory scale and require interdisciplinary collaboration from various disciplines of physics, chemistry, biology, materials science and engineering. Another difficulty arises from measurements. Since sizes of nanomaterials are supposed to be tiny, the signal to noise ratio is low so as to make it difficult to measure unless the resolution of apparatus is improved. Furthermore, hybrid nanostructures require multimodal measurement tools in order to reveal multifunctions. In this regard, it is necessary to develop a new system combined with several apparatus with high spatial resolution and high sensitivity.