IBS Publications Repository: Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library

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IBS Publications RepositoryCenter for Self-assembly and Complexity(복잡계 자기조립 연구단)1. Journal Papers (저널논문)

Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library

DC Field	Value	Language
dc.contributor.author	Naoki Miyamoto	-
dc.contributor.author	Go, Young-Hyun	-
dc.contributor.author	Larissa Miasiro Ciaramicoli	-
dc.contributor.author	Haw-Young Kwon	-
dc.contributor.author	Kim, Heon Seok	-
dc.contributor.author	Bi, Xuezhi	-
dc.contributor.author	Yu, Young Hyun	-
dc.contributor.author	Kim, Beomsue	-
dc.contributor.author	Ha, Hyung-Ho	-
dc.contributor.author	Kang, Nam-Young	-
dc.contributor.author	Yun, Seong-Wook	-
dc.contributor.author	Jin-Soo Kim	-
dc.contributor.author	Cha, Hyuk-Jin	-
dc.contributor.author	Young-Tae Chang	-
dc.date.accessioned	2022-01-04T07:50:03Z	-
dc.date.available	2022-01-04T07:50:03Z	-
dc.date.created	2021-12-20	-
dc.date.issued	2021-12	-
dc.identifier.issn	2633-0679	-
dc.identifier.uri	https://pr.ibs.re.kr/handle/8788114/10992	-
dc.description.abstract	© The Royal Society of Chemistry.CDy1 is a powerful tool to distingusih embryonic stem cells for reprogramming studies and regeneration medicine. However, the stem cell selectivity mechanism of CDy1 has not been fully understood. Here, we report ALDH2 and ABCB1 as the molecular targets of CDy1, elucidated by live-cell affinity-matrix and ABC transporter CRISPRa library screening. The two unique orthogonal mechanisms provide the potential of multi-demensional cellular distinction of specific cell types.	-
dc.language	영어	-
dc.publisher	Royal Society of Chemistry	-
dc.title	Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library	-
dc.type	Article	-
dc.type.rims	ART	-
dc.identifier.scopusid	2-s2.0-85120739299	-
dc.identifier.rimsid	76954	-
dc.contributor.affiliatedAuthor	Naoki Miyamoto	-
dc.contributor.affiliatedAuthor	Larissa Miasiro Ciaramicoli	-
dc.contributor.affiliatedAuthor	Haw-Young Kwon	-
dc.contributor.affiliatedAuthor	Jin-Soo Kim	-
dc.contributor.affiliatedAuthor	Young-Tae Chang	-
dc.identifier.doi	10.1039/d1cb00147g	-
dc.identifier.bibliographicCitation	RSC Chemical Biology, v.2, no.6, pp.1590 - 1593	-
dc.relation.isPartOf	RSC Chemical Biology	-
dc.citation.title	RSC Chemical Biology	-
dc.citation.volume	2	-
dc.citation.number	6	-
dc.citation.startPage	1590	-
dc.citation.endPage	1593	-
dc.description.journalClass	1	-
dc.description.journalClass	1	-
dc.description.isOpenAccess	N	-
dc.description.journalRegisteredClass	scopus	-