BROWSE

Related Scientist

Researcher

뇌과학이미징연구단
뇌과학 이미징 연구단
more info

Dual MRI T-1 and T-2(()*()) contrast with size-controlled iron oxide nanoparticles

Cited 19 time in webofscience Cited 0 time in scopus
499 Viewed 25 Downloaded
Title
Dual MRI T-1 and T-2(()*()) contrast with size-controlled iron oxide nanoparticles
Author(s)
Jung, H; Park, B; Lee, C; Cho, J; Suh, J; Jang-Yeon Park; Kim, Y; Kim, J; Cho, G; Cho, H
Publication Date
2014-11
Journal
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, v.10, no.8, pp.1679 - 1689
Publisher
ELSEVIER SCIENCE BV
Abstract
Contrast-enhancing magnetic resonance mechanism, employing either positive or negative signal changes, has contrast-specific signal characteristics. Although highly sensitive, negative contrast typically decreases the resolution and spatial specificity of MRI, whereas positive contrast lacks a high contrast-to-noise ratio but offers high spatial accuracy. To overcome these individual limitations, dual-contrast acquisitions were performed using iron oxide nanoparticles and a pair of MRI acquisitions. Specifically, vascular signals in MR angiography were positively enhanced using ultrashort echo (UTE) acquisition, which provided highly resolved vessel structures with increased vessel/ tissue contrast. In addition, fast low angle shot (FLASH) acquisition yielded strong negative vessel contrast, resulting in the higher number of discernible vessel branches than those obtained from the UTE method. Taken together, the high sensitivity of the negative contrast delineated ambiguous vessel regions, whereas the positive contrast effectively eliminated the false negative contrast areas (e.g., airways and bones), demonstrating the benefits of the dual-contrast method.
URI
https://pr.ibs.re.kr/handle/8788114/871
ISSN
1549-9634
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > Journal Papers (저널논문)
Files in This Item:
021_(Nanomedicine)_Dual MRI T1 and T2.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse