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뇌과학이미징연구단
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Dual MRI T-1 and T-2(()*()) contrast with size-controlled iron oxide nanoparticles

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dc.contributor.authorJung, H-
dc.contributor.authorPark, B-
dc.contributor.authorLee, C-
dc.contributor.authorCho, J-
dc.contributor.authorSuh, J-
dc.contributor.authorJang-Yeon Park-
dc.contributor.authorKim, Y-
dc.contributor.authorKim, J-
dc.contributor.authorCho, G-
dc.contributor.authorCho, H-
dc.date.available2015-04-20T05:20:59Z-
dc.date.created2015-01-21-
dc.date.issued2014-11-
dc.identifier.issn1549-9634-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/871-
dc.description.abstractContrast-enhancing magnetic resonance mechanism, employing either positive or negative signal changes, has contrast-specific signal characteristics. Although highly sensitive, negative contrast typically decreases the resolution and spatial specificity of MRI, whereas positive contrast lacks a high contrast-to-noise ratio but offers high spatial accuracy. To overcome these individual limitations, dual-contrast acquisitions were performed using iron oxide nanoparticles and a pair of MRI acquisitions. Specifically, vascular signals in MR angiography were positively enhanced using ultrashort echo (UTE) acquisition, which provided highly resolved vessel structures with increased vessel/ tissue contrast. In addition, fast low angle shot (FLASH) acquisition yielded strong negative vessel contrast, resulting in the higher number of discernible vessel branches than those obtained from the UTE method. Taken together, the high sensitivity of the negative contrast delineated ambiguous vessel regions, whereas the positive contrast effectively eliminated the false negative contrast areas (e.g., airways and bones), demonstrating the benefits of the dual-contrast method.-
dc.description.uri1-
dc.language영어-
dc.publisherELSEVIER SCIENCE BV-
dc.subjectSPION-
dc.subjectDual MR T1 and T2⁎ contrast agent-
dc.subjectMR angiography-
dc.titleDual MRI T-1 and T-2(()*()) contrast with size-controlled iron oxide nanoparticles-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000344939700010-
dc.identifier.scopusid2-s2.0-84908565636-
dc.identifier.rimsid16819ko
dc.date.tcdate2018-10-01-
dc.contributor.affiliatedAuthorJang-Yeon Park-
dc.identifier.doi10.1016/j.nano.2014.05.003-
dc.identifier.bibliographicCitationNANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, v.10, no.8, pp.1679 - 1689-
dc.citation.titleNANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE-
dc.citation.volume10-
dc.citation.number8-
dc.citation.startPage1679-
dc.citation.endPage1689-
dc.date.scptcdate2018-10-01-
dc.description.wostc19-
dc.description.scptc20-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.subject.keywordPlusMAGNETIC-RESONANCE ANGIOGRAPHY-
dc.subject.keywordPlusBLOOD-VOLUME-
dc.subject.keywordPlusIN-VIVO-
dc.subject.keywordPlusWATER EXCHANGE-
dc.subject.keywordPlusAGENTS-
dc.subject.keywordPlusFERUMOXYTOL-
dc.subject.keywordPlusENHANCEMENT-
dc.subject.keywordPlusMODEL-
dc.subject.keywordPlusBRAIN-
dc.subject.keywordPlusQUANTIFICATION-
dc.subject.keywordAuthorSPION-
dc.subject.keywordAuthorDual MR T-1 and T-2* contrast agent-
dc.subject.keywordAuthorMR angiography-
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
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