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복잡계 자기조립 연구단
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Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder

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Title
Verification of the Functional Antioxidant Activity and Antimelanogenic Properties of Extracts of Poria cocos Mycelium Fermented with Freeze-Dried Plum Powder
Author(s)
Kang K.-Y.; Hwang Y.-H.; Lee S.-J.; Jang H.-Y.; Hong S.-G.; Mun S.-K.; Kim S.-J.; Jong-Jin Kim; Park K.-W.; Seo K.-S.; Ban S.-E.; Jin S.-W.; Kim H.-J.; Yee S.-T.
Publication Date
2019
Journal
International Journal of Biomaterials, v.2019, no., pp.9283207 -
Publisher
Hindawi Publishing Corporation
Abstract
© 2019 Kyung-Yun Kang et al.Here we examine the effects of extracts of Poria cocos mycelium fermented with freeze-dried plum powder (PPE) on the α-melanocyte stimulating hormone (α-MSH)-stimulated melanogenesis in cultured murine B16 melanoma cells (B16 cells), relative to the effects of Prunus extract. We found that an extract of Prunus fermentation showed significant inhibition of melanogenesis and tyrosinase activity with no effect on cell proliferation and was more active compared to Prunus extract alone. Furthermore, we confirmed that medium containing 3% Prunus was the optimal culture substrate for fermentation with Poria cocos. These results provide evidence that Prunus fermentation extract affects skin whiting in murine B16 melanoma cells (B16 cells). Prunus contains rutin, oxalic acid, succinic acid, and fumaric acid, which help in digestion and fatigue recovery. The rutin of Prunus mume is reported to have antioxidant and anti-inflammatory effects. Also, Prunus extract has a tyrosinase inhibitory activity for skin whiting through its antioxidant activity. Therefore, we believe the Prunus extract for Poria cocos fermentation can be provided as a potential mediator to induce skin whiting
URI
https://pr.ibs.re.kr/handle/8788114/6183
ISSN
1687-8787
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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