Development of a Universal Fluorescent Probe for Gram-Positive Bacteria

Cited 0 time in webofscience Cited 0 time in scopus
20 Viewed 6 Downloaded
Title
Development of a Universal Fluorescent Probe for Gram-Positive Bacteria
Author(s)
Haw-Young Kwon; Xiao Liu; Eun Gyeong Choi; Jung Yeol Lee; So-Young Choi; Jun-Young Kim; Lu Wang; Sung-Jin Park; Beomsue Kim; Yong-An Lee; Jong Jin Kim; Nam Young Kang; Young Tae Chang
Publication Date
2019-06
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.58, no.25, pp.8426 - 8431
Publisher
WILEY-V C H VERLAG GMBH
Abstract
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The rapid and sensitive classification of bacteria is the first step of bacterial community research and the treatment of infection. Herein, a fluorescent probe BacGO is presented, which shows the best universal selectivity for Gram-positive bacteria among known probes with a minimum staining procedure for sample detection and enrichment of the live bacteria. BacGO could also be used to assess of the Gram status in the bacterial community from wastewater sludge. Furthermore, BacGO could sensitively and selectively detect a Gram-positive bacterial infection, not only in vitro but also using an in vivo keratitis mouse model. BacGO provides an unprecedented research tool for the study of dynamic bacterial communities and for clinical application
URI
https://pr.ibs.re.kr/handle/8788114/6098
ISSN
1433-7851
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
Files in This Item:
Kwon_et_al-2019-Angewandte_Chemie_International_Edition.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse