Oscillating droplet trains in microfluidic networks and their suppression in blood flow

Cited 0 time in webofscience Cited 0 time in scopus
44 Viewed 11 Downloaded
Title
Oscillating droplet trains in microfluidic networks and their suppression in blood flow
Author(s)
Olgierd Cybulski; Piotr Garstecki; Bartosz A. Grzybowski
Publication Date
2019-07
Journal
NATURE PHYSICS, v.15, no.7, pp.706 - 713
Publisher
NATURE PUBLISHING GROUP
Abstract
© 2019, The Author(s), under exclusive licence to Springer Nature Limited. Droplets forming sequences in simple microfluidic networks are known to exhibit complex behaviours, but their dynamics are yet to be probed in channels long enough to accommodate many droplets simultaneously. Here we show that uniform sequences of liquid droplets flowing through microfluidic networks can spontaneously form ‘trains’ that periodically exchange between different branches of the network. Such system-wide oscillations do not rely on direct droplet–droplet interactions, are common to networks of various topologies, can be controlled or eliminated by adjusting network dimensions and can synchronize into larger flow patterns. The oscillations can also be suppressed via droplet collisions at diverging junctions. This mechanism may explain why red blood cells in microcapillaries exhibit only low-amplitude oscillations, preventing dangerous local hypertension or hypoxia that might otherwise ensue. Our findings are substantiated by a theoretical model that treats droplets as sets of moving points in one-dimensional ducts and captures the dynamics of large droplet ensembles without invoking the microscopic details of flows in or around the droplets. For blood flow, this simplified description offers more realistic estimates than continuous haemodynamic models, indicating the relevance of the discrete nature of blood to the excitation of oscillations
URI
https://pr.ibs.re.kr/handle/8788114/5964
ISSN
1745-2473
Appears in Collections:
Center for Soft and Living Matter(첨단연성물질 연구단) > Journal Papers (저널논문)
Files in This Item:
2019_Bartosz_Nat.Phys._Oscillating droplet trains in microfluidic networks and their suppression in blood flow.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse