Propagation of oscillating chemical signals through reaction networks

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Title
Propagation of oscillating chemical signals through reaction networks
Author(s)
Rafal Roszak; Michal Bajczyk; Ewa Gajewska; Robert Holyst; Bartosz Grzybowski
Publication Date
2019-03
Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.58, no.14, pp.4520 - 4525
Publisher
WILEY-V C H VERLAG GMBH
Abstract
Akin to electronic systems that can tune to and process signals of select frequencies, systems/networks of chemical reactions also „propagate“ time‐varying concentration inputs in a frequency‐dependent manner. Whereas signals of low frequencies are transmitted, higher frequency inputs are dampened and converted into steady‐concentration outputs. Such behavior is observed in both idealized reaction chains as well as realistic signalling cascades, in the latter case explaining the experimentally observed responses of such cascades to input calcium oscillations. These and other results are supported by numerical simulations within the freely available Kinetix web application we developed to study chemical systems of arbitrary architectures, reaction kinetics, and boundary conditions. (c) 2013 Weily-VCH Verlag GmbH & Co. KgaA, Weinheim
URI
https://pr.ibs.re.kr/handle/8788114/5679
ISSN
1433-7851
Appears in Collections:
Center for Soft and Living Matter(첨단연성물질 연구단) > Journal Papers (저널논문)
Files in This Item:
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