CDy14: a novel biofilm probe targeting exopolysaccharide Psl

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Title
CDy14: a novel biofilm probe targeting exopolysaccharide Psl
Author(s)
Haw-Young Kwon; Jun-Young Kim; Jung Yeol Lee; Joey Kuok Hoong Yam; Louis-Jin Hultqvist; Wang Xu; Morten Rybtke; Tim Tolker-Nielsen; Jong-Jin Kim; Nam-Young Kang; Liang Yang; Sung-Jin Park; Michael Givsko; Young-Tae Chang
Publication Date
2018-10
Journal
CHEMICAL COMMUNICATIONS, v.54, no.84, pp.11865 - 11868
Publisher
ROYAL SOC CHEMISTRY
Abstract
Detection of biofilm bacteria would be an ideal method for the physicians to diagnose chronic bacterial infections directly, but there are few imaging probes available so far. Here, we report the development of a novel biofilm detecting fluorescent probe, CDy14, through an unbiased screening of a fluorescence library and elucidated its binding partner Psl, an exopolysaccharide of the biofilm. ©The Royal Society of Chemistry 2018
URI
https://pr.ibs.re.kr/handle/8788114/5111
ISSN
1359-7345
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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