Dual functional membrane capable of both visual sensing and blocking of waterborne virus

Cited 0 time in webofscience Cited 0 time in scopus
23 Viewed 15 Downloaded
Title
Dual functional membrane capable of both visual sensing and blocking of waterborne virus
Author(s)
Lee B.-Y.; Jinhwan Kim; Won Jong Kim; Kim J.K.
Publication Date
2018-03
Journal
JOURNAL OF MEMBRANE SCIENCE, v.549, no., pp.680 - 685
Publisher
ELSEVIER SCIENCE BV
Abstract
Norovirus, which is transmitted by contact with a contaminated object or person who has a norovirus infection, eating contaminated food, or drinking contaminated water, is a highly contagious virus for humans and animals. Among many infection routes, water supply systems from reservoirs or dams become very important due to the possibility of mass infection. Because only a small amount of norovirus (10–100 particles forming unit) can cause the infection, a rapid and easy detection of the virus is required. Once norovirus is detected, the water supply should be quickly shut down. Here, we introduce a dual functional membrane capable of both easy detecting with the naked eye and blocking noroviruses. We employed an anodized aluminum oxide (AAO) membrane with uniform pores. The top and bottom parts of the membrane were grafted with polydiacetylene (PDA) and poly(N-isopropylacrylamide) (PNIPAM), respectively. The top part was further bioconjugated by antibody for feline calicivirus (FCV), which is a model virus whose structure is similar to norovirus. The membrane showed color change from blue to red when the FCVs were attached to the antibodies. Water flux was controlled (turned on and off) by changing water temperature by using the well-known thermosensitive property of PNIPAM chains. On and off control of water flow was quickly established (less than 5 s) when a laser with near infrared (NIR) wavelength was turned on and off, respectively. In addition, the membrane completely blocked the virus influx into the water system by antibody binding before visual sensing followed by flow control. © 2017 Elsevier B.V
URI
https://pr.ibs.re.kr/handle/8788114/5003
ISSN
0376-7388
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
Files in This Item:
04.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse