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Overcoming Depression by Inhibition of Neural Burst Firing

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Title
Overcoming Depression by Inhibition of Neural Burst Firing
Author(s)
Daesoo Kim; Eunji Cheong; Hee-Sup Shin
Publication Date
2018-06
Journal
Neuron, v.98, no.5, pp.878 - 879
Publisher
CELL PRESS
Abstract
The N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine has been found to have rapid and long-lasting antidepressive effects. Two elegant studies from Hailan Hu's laboratory (Cui et al., 2018; Yang et al., 2018) showed that ketamine blocks burst firing of neurons in the lateral habenula (LHb), rapidly relieving symptoms of depression. The N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine has been found to have rapid and long-lasting antidepressive effects. Two elegant studies from Hailan Hu's laboratory (Cui et al., 2018; Yang et al., 2018) showed that ketamine blocks burst firing of neurons in the lateral habenula (LHb), rapidly relieving symptoms of depression. © 2018 Elsevier Inc
URI
https://pr.ibs.re.kr/handle/8788114/4483
ISSN
0896-6273
Appears in Collections:
Center for Cognition and Sociality(인지 및 사회성 연구단) > Journal Papers (저널논문)
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