In Vivo Imaging of CNS Injury and Disease

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Title
In Vivo Imaging of CNS Injury and Disease
Author(s)
Katerina Akassoglou; Mario Merlini; Victoria A. Rafalski; Raquel Real; Liang Liang; Yunju Jin; Sarah E. Dougherty; Vincenzo De Paola; David J. Linden; Thomas Misgeld; Binhai Zheng
Publication Date
2017-11
Journal
JOURNAL OF NEUROSCIENCE, v.37, no.45, pp.10808 - 10816
Publisher
SOC NEUROSCIENCE
Abstract
In vivo optical imaging has emerged as a powerful tool with which to study cellular responses to injury and disease in the mammalian CNS. Important new insights have emerged regarding axonal degeneration and regeneration, glial responses and neuroinflammation, changes in the neurovascular unit, and, more recently, neural transplantations. Accompanying a 2017 SfN Mini-Symposium, here, we discuss selected recent advances in understanding the neuronal, glial, and other cellular responses to CNS injury and disease with in vivo imaging of the rodent brain or spinal cord. We anticipate that in vivo optical imaging will continue to be at the forefront of breakthrough discoveries of fundamental mechanisms and therapies for CNS injury and disease. © 2017 the authors
URI
https://pr.ibs.re.kr/handle/8788114/4003
ISSN
0270-6474
Appears in Collections:
Center for Cognition and Sociality(인지 및 사회성 연구단) > Journal Papers (저널논문)
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