Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection

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Title
Removal of back-reflection noise at ultrathin imaging probes by the single-core illumination and wide-field detection
Author(s)
Changhyeong Yoon; Munkyu Kang; Jin. H. Hong; Taeseok D. Yang; Jingchao Xing; Hongki Yoo; Youngwoon Choi; Wonshik Choi
Publication Date
2017-07
Journal
SCIENTIFIC REPORTS, v.7, no.1, pp.6524 -
Publisher
NATURE PUBLISHING GROUP
Abstract
Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propose a method to spatially isolate illumination pathways from detection channels, and demonstrate wide-field reflectance imaging free from back-reflection noise. In the image fiber bundle, we send illumination light through individual core fibers and detect signals from target objects through the other fibers. The transmission matrix of the fiber bundle is measured and used to reconstruct a pixelation-free image. We demonstrated that the proposed imaging method improved 3.2 times on the signal to noise ratio produced by the conventional illumination-detection scheme. © 2017 The Author(s)
URI
https://pr.ibs.re.kr/handle/8788114/3807
ISSN
2045-2322
Appears in Collections:
Center for Molecular Spectroscopy and Dynamics(분자 분광학 및 동력학 연구단) > Journal Papers (저널논문)
Files in This Item:
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