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Park, Kyeng Min
복잡계 자기조립 연구단
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Ultrastable artificial binding pairs as a supramolecular latching system: A next generation chemical tool for proteomics

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Title
Ultrastable artificial binding pairs as a supramolecular latching system: A next generation chemical tool for proteomics
Author(s)
Kyeng Min Park; James Murray; Kimoon Kim
Subject
HOST-GUEST, ; COMPLEXES, ; AVIDIN, ; BIOTIN, ; LIGAND
Publication Date
2017-03
Journal
ACCOUNTS OF CHEMICAL RESEARCH, v.50, no.3, pp.644 - 646
Publisher
AMER CHEMICAL SOC
Abstract
In this Commentary, we discuss cucurbit[7]uril-based ultrastable artificial binding pairs as a supramolecular latching system and how we envision this becoming important tools in proteomics. The limitations of current proteomic techniques are described with an emphasis on the lack of tools to answer questions about the complex and dynamic nature of the proteome. Our thoughts as to how artificial ultrastable binding pairs may be able to address these questions are given especially when they are combined with existing methods. © 2017 American Chemical Society. © 2017 American Chemical Society
URI
https://pr.ibs.re.kr/handle/8788114/3761
DOI
10.1021/acs.accounts.6b00645
ISSN
0001-4842
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > 1. Journal Papers (저널논문)
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