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IBS Publications RepositoryCenter for Self-assembly and Complexity(복잡계 자기조립 연구단)1. Journal Papers (저널논문)
Light-Induced Acid Generation on a Gatekeeper for Smart Nitric Oxide Delivery
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Hyung Woo Choi | - |
| dc.contributor.author | Jihoon Kim | - |
| dc.contributor.author | Kim J. | - |
| dc.contributor.author | Yonghwi Kim | - |
| dc.contributor.author | Song H.B. | - |
| dc.contributor.author | Kim J.H. | - |
| dc.contributor.author | Kimoon Kim | - |
| dc.contributor.author | Won Jong Kim | - |
| dc.date.available | 2016-07-19T07:40:09Z | - |
| dc.date.created | 2016-06-20 | - |
| dc.date.issued | 2016-04 | - |
| dc.identifier.issn | 1936-0851 | - |
| dc.identifier.uri | https://pr.ibs.re.kr/handle/8788114/2679 | - |
| dc.description.abstract | We report herein the design of a light-responsive gatekeeper for smart nitric oxide (NO) delivery. The gatekeeper is composed of a pH-jump reagent as an intermediary of stimulus and a calcium phosphate (CaP) coating as a shielding layer for NO release. The light irradiation and subsequent acid generation are used as triggers for uncapping the gatekeeper and releasing NO. The acids generated from a light-activated pH-jump agent loaded in the mesoporous nanoparticles accelerated the degradation of the CaP-coating layers on the nanoparticles, facilitating the light-responsive NO release from diazeniumdiolate by exposing a NO donor to physiological conditions. Using the combination of the pH-jump reagent and CaP coating, we successfully developed a light-responsive gatekeeper system for spatiotemporal-controlled NO delivery. © 2016 American Chemical Society | - |
| dc.description.uri | 1 | - |
| dc.language | 영어 | - |
| dc.publisher | AMER CHEMICAL SOC | - |
| dc.subject | calcium phosphate | - |
| dc.subject | corneal wound healing | - |
| dc.subject | gatekeeper | - |
| dc.subject | nitric oxide delivery | - |
| dc.subject | pH-jump reagent | - |
| dc.title | Light-Induced Acid Generation on a Gatekeeper for Smart Nitric Oxide Delivery | - |
| dc.type | Article | - |
| dc.type.rims | ART | - |
| dc.identifier.wosid | 000375245000036 | - |
| dc.identifier.scopusid | 2-s2.0-84968735648 | - |
| dc.identifier.rimsid | 55857 | ko |
| dc.date.tcdate | 2018-10-01 | - |
| dc.contributor.affiliatedAuthor | Hyung Woo Choi | - |
| dc.contributor.affiliatedAuthor | Jihoon Kim | - |
| dc.contributor.affiliatedAuthor | Yonghwi Kim | - |
| dc.contributor.affiliatedAuthor | Kimoon Kim | - |
| dc.contributor.affiliatedAuthor | Won Jong Kim | - |
| dc.identifier.doi | 10.1021/acsnano.5b07483 | - |
| dc.identifier.bibliographicCitation | ACS NANO, v.10, no.4, pp.4199 - 4208 | - |
| dc.citation.title | ACS NANO | - |
| dc.citation.volume | 10 | - |
| dc.citation.number | 4 | - |
| dc.citation.startPage | 4199 | - |
| dc.citation.endPage | 4208 | - |
| dc.date.scptcdate | 2018-10-01 | - |
| dc.description.wostc | 26 | - |
| dc.description.scptc | 25 | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.subject.keywordAuthor | calcium phosphate | - |
| dc.subject.keywordAuthor | corneal wound healing | - |
| dc.subject.keywordAuthor | gatekeeper | - |
| dc.subject.keywordAuthor | nitric oxide delivery | - |
| dc.subject.keywordAuthor | pH-jump reagent | - |
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