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Challenges and Opportunities of Centrifugal Microfluidics for Extreme Point-of-Care Testing

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Title
Challenges and Opportunities of Centrifugal Microfluidics for Extreme Point-of-Care Testing
Author(s)
Michael, IJ; Kim, TH; Sunkara, V; Yoon-Kyoung Cho
Subject
diagnostics, ; centrifugal microfluidics, ; point-of-care, ; developing countries, ; clinical chemistry, ; immunoassays, ; nucleic acid tests
Publication Date
2016-02
Journal
MICROMACHINES, v.7, no.2, pp.32
Publisher
MDPI AG
Abstract
The advantages offered by centrifugal microfluidic systems have encouraged its rapid adaptation in the fields of in vitro diagnostics, clinical chemistry, immunoassays, and nucleic acid tests. Centrifugal microfluidic devices are currently used in both clinical and point-of-care settings. Recent studies have shown that this new diagnostic platform could be potentially used in extreme point-of-care settings like remote villages in the Indian subcontinent and in Africa. Several technological inventions have decentralized diagnostics in developing countries; however, very few microfluidic technologies have been successful in meeting the demand. By identifying the finest difference between the point-of-care testing and extreme point-of-care infrastructure, this review captures the evolving diagnostic needs of developing countries paired with infrastructural challenges with technological hurdles to healthcare delivery in extreme point-of-care settings. In particular, the requirements for making centrifugal diagnostic devices viable in developing countries are discussed based on a detailed analysis of the demands in different clinical settings including the distinctive needs of extreme point-of-care settings. © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
URI
https://pr.ibs.re.kr/handle/8788114/2491
DOI
10.3390/mi7020032
ISSN
2072-666X
Appears in Collections:
Center for Soft and Living Matter(첨단연성물질 연구단) > 1. Journal Papers (저널논문)
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