Synergistic nanomedicine by combined gene and photothermal therapy Highly Cited Paper

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Title
Synergistic nanomedicine by combined gene and photothermal therapy
Author(s)
Kim J.; Jihoon Kim; Jeong C.; Won Jong Kim
Publication Date
2016-03
Journal
ADVANCED DRUG DELIVERY REVIEWS, v.98, no., pp.99 - 112
Publisher
ELSEVIER SCIENCE BV
Abstract
To date, various nanomaterials with the ability for gene delivery or photothermal effect have been developed in the field of biomedicine. The therapeutic potential of these nanomaterials has raised considerable interests in their use in potential next-generation strategies for effective anticancer therapy. In particular, the advancement of novel nanomedicines utilizing both therapeutic strategies of gene delivery and photothermal effect has generated much optimism regarding the imminent development of effective and successful cancer treatments. In this review, we discuss current research progress with regard to combined gene and photothermal therapy. This review focuses on synergistic therapeutic systems combining gene regulation and photothermal ablation as well as logically designed nano-carriers aimed at enhancing the delivery efficiency of therapeutic genes using the photothermal effect. The examples detailed in this review provide insight to further our understanding of combinatorial gene and photothermal therapy, thus paving the way for the design of promising nanomedicines. © 2015
URI
https://pr.ibs.re.kr/handle/8788114/2486
ISSN
0169-409X
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
Files in This Item:
1-s2.0-S0169409X15300247-main 복잡계 advanced drug delivery reviews.pdfDownload

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