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Emerging techniques in the isolation and characterization of extracellular vesicles and their roles in cancer diagnostics and prognostics

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Title
Emerging techniques in the isolation and characterization of extracellular vesicles and their roles in cancer diagnostics and prognostics
Author(s)
Vijaya Sunkara; Hyun-Kyung Woo; Yoon-Kyoung Cho
Publication Date
2016-01
Journal
ANALYST, v.141, no.2, pp.371 - 381
Publisher
ROYAL SOC CHEMISTRY
Abstract
Extracellular vesicles (EVs) are cell-derived nanovesicles, present in almost all types of body fluids, which play an important role in intercellular communication and are involved in the transport of biological signals for regulating diverse cellular functions. Due to the increasing clinical interest in the role of EVs in tumor promotion, various techniques for their isolation, detection, and characterization are being developed. In this review, we present an overview of the current EV isolation and characterization methods in addition to their applications and limitations. Furthermore, EVs as the potential emerging biomarkers in cancer management and their clinical implementation are briefly discussed. © The Royal Society of Chemistry 2016
URI
https://pr.ibs.re.kr/handle/8788114/2207
ISSN
0003-2654
Appears in Collections:
Center for Soft and Living Matter(첨단연성물질 연구단) > Journal Papers (저널논문)
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