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Gurusamy Saravanakumar
복잡계 자기조립 연구단
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Visible light-induced singlet oxygen-mediated intracellular disassembly of polymeric micelles co-loaded with a photosensitizer and an anticancer drug for enhanced photodynamic therapy

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Title
Visible light-induced singlet oxygen-mediated intracellular disassembly of polymeric micelles co-loaded with a photosensitizer and an anticancer drug for enhanced photodynamic therapy
Author(s)
Gurusamy Saravanakumar; Junseok Lee; Jihoon Kim; Won Jong Kim
Publication Date
2015-06
Journal
CHEMICAL COMMUNICATIONS, v.51, no.49, pp.9995 - 9998
Publisher
ROYAL SOC CHEMISTRY
Abstract
Herein, we report a biocompatible amphiphilic block copolymer micelle bearing a singlet oxygen-sensitive vinyldithioether cleavable linker at the core-shell junction, which undergoes singlet oxygen-mediated photocleavage in the presence of visible light. The micelle facilitates the light-responsive release of singlet oxygen and an anticancer drug for enhanced photodynamic therapy
URI
https://pr.ibs.re.kr/handle/8788114/2002
ISSN
1359-7345
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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