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나노입자연구단
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Minimally-Invasive and In-Vivo Hydrogel Patterning Method for In Situ Fabrication of Implantable Hydrogel Devices

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dc.contributor.authorGi Doo Cha-
dc.contributor.authorMinjeong Kim-
dc.contributor.authorOk Kyu Park-
dc.contributor.authorSung-Hyuk Sunwoo-
dc.contributor.authorTaegyu Kang-
dc.contributor.authorWang Hee Lee-
dc.contributor.authorSeonghyeon Nam-
dc.contributor.authorTaeghwan Hyeon-
dc.contributor.authorSeung Hong Choi-
dc.contributor.authorDae-Hyeong Kim-
dc.date.accessioned2023-12-29T22:01:18Z-
dc.date.available2023-12-29T22:01:18Z-
dc.date.created2023-05-30-
dc.date.issued2023-09-
dc.identifier.issn2366-9608-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/14432-
dc.description.abstractDespite advances in a wide range of device applications of hydrogels, including implantable ones, a method for deploying patterned hydrogel devices into the body in a minimally-invasive manner is not available yet. However, in situ patterning of the hydrogel in vivo has an obvious advantage, by which incision surgery for implantation of the hydrogel device can be avoided. Here, a minimally-invasive and in vivo hydrogel patterning method for in situ fabrication of implantable hydrogel devices is presented. The sequential application of injectable hydrogels and enzymes, with assistance of minimally-invasive surgical instruments, enables the in vivo and in situ hydrogel patterning. This patterning method can be achieved by adopting an appropriate combination of the sacrificial mold hydrogel and the frame hydrogel, in consideration of unique material properties of the hydrogels such as high softness, facile mass transfer, biocompatibility, and diverse crosslinking mechanisms. In vivo and in situ patterning of the hydrogels functionalized with nanomaterials is also demonstrated to fabricate the wireless heater and tissue scaffold, showcasing broad applicability of the patterning method.-
dc.language영어-
dc.publisherWILEY-V C H VERLAG GMBH-
dc.titleMinimally-Invasive and In-Vivo Hydrogel Patterning Method for In Situ Fabrication of Implantable Hydrogel Devices-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000989107500001-
dc.identifier.scopusid2-s2.0-85159596790-
dc.identifier.rimsid80850-
dc.contributor.affiliatedAuthorGi Doo Cha-
dc.contributor.affiliatedAuthorMinjeong Kim-
dc.contributor.affiliatedAuthorOk Kyu Park-
dc.contributor.affiliatedAuthorSung-Hyuk Sunwoo-
dc.contributor.affiliatedAuthorTaegyu Kang-
dc.contributor.affiliatedAuthorWang Hee Lee-
dc.contributor.affiliatedAuthorSeonghyeon Nam-
dc.contributor.affiliatedAuthorTaeghwan Hyeon-
dc.contributor.affiliatedAuthorSeung Hong Choi-
dc.contributor.affiliatedAuthorDae-Hyeong Kim-
dc.identifier.doi10.1002/smtd.202300032-
dc.identifier.bibliographicCitationSMALL METHODS, v.7, no.9-
dc.relation.isPartOfSMALL METHODS-
dc.citation.titleSMALL METHODS-
dc.citation.volume7-
dc.citation.number9-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.subject.keywordPlusACTUATION-
dc.subject.keywordPlusSOFT-
dc.subject.keywordAuthorhydrogel nanocomposites-
dc.subject.keywordAuthorimplantable devices-
dc.subject.keywordAuthorin situ patterning-
dc.subject.keywordAuthorin vivo applications-
dc.subject.keywordAuthorminimally-invasive methods-
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > 1. Journal Papers (저널논문)
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