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In Vivo Sol–Gel Reaction of Tantalum Alkoxide for Endovascular Embolization

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dc.contributor.authorGiho Ko-
dc.contributor.authorChoi, Jin Woo-
dc.contributor.authorKwangsoo Shin-
dc.contributor.authorYoung Geon Kim-
dc.contributor.authorTaegyu Kang-
dc.contributor.authorDokyoon Kim-
dc.contributor.authorNohyun Lee-
dc.contributor.authorKim, Hyo-Cheol-
dc.contributor.authorTaeghwan Hyeon-
dc.date.accessioned2022-07-29T07:51:24Z-
dc.date.available2022-07-29T07:51:24Z-
dc.date.created2021-12-15-
dc.date.issued2022-02-
dc.identifier.issn2192-2640-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/12063-
dc.description.abstract© 2021 Wiley-VCH GmbHLiquid embolic agents are considered the most promising for various embolization procedures because they enable deep penetration. For realizing effective procedures, the delivery of liquid embolic agents should be guided under X-ray imaging systems and the solidification time should be optimized for the specific indication. The biocompatibility of embolic agents is also crucial because they remain in the vessel after embolization. In this study, new biocompatible embolic agents based on tantalum ethoxide is synthesized. Tantalum alkoxide liquid embolics (TALE) possess the radiopacity for fluoroscopy and can control the penetration depth by modifying the sol–gel kinetics. Furthermore, TALE can serve as drug carriers for synergistic treatment. Using these excellent characteristics, it is demonstrated that TALE agents can be used in various situations including the transarterial chemoembolization of hepatocellular carcinoma and embolotherapy of massive bleeding from the femoral artery.-
dc.language영어-
dc.publisherJohn Wiley and Sons Inc-
dc.titleIn Vivo Sol–Gel Reaction of Tantalum Alkoxide for Endovascular Embolization-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000722264300001-
dc.identifier.scopusid2-s2.0-85119661240-
dc.identifier.rimsid76860-
dc.contributor.affiliatedAuthorGiho Ko-
dc.contributor.affiliatedAuthorKwangsoo Shin-
dc.contributor.affiliatedAuthorYoung Geon Kim-
dc.contributor.affiliatedAuthorTaegyu Kang-
dc.contributor.affiliatedAuthorDokyoon Kim-
dc.contributor.affiliatedAuthorNohyun Lee-
dc.contributor.affiliatedAuthorTaeghwan Hyeon-
dc.identifier.doi10.1002/adhm.202101908-
dc.identifier.bibliographicCitationAdvanced Healthcare Materials, v.11, no.4-
dc.relation.isPartOfAdvanced Healthcare Materials-
dc.citation.titleAdvanced Healthcare Materials-
dc.citation.volume11-
dc.citation.number4-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryEngineering, Biomedical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Biomaterials-
dc.subject.keywordPlusOXIDE NANOPARTICLES-
dc.subject.keywordPlusCHEMOEMBOLIZATION-
dc.subject.keywordAuthorcancer-
dc.subject.keywordAuthorembolization-
dc.subject.keywordAuthorHCC-
dc.subject.keywordAuthorliquid embolic agents-
dc.subject.keywordAuthorminimally invasive procedures-
dc.subject.keywordAuthorsol–gel reaction-
Appears in Collections:
Center for Nanoparticle Research(나노입자 연구단) > 1. Journal Papers (저널논문)
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