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A platform for nitric oxide delivery

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Title
A platform for nitric oxide delivery
Author(s)
Jihoon Kim; Gurusamy Saravanakumar; Hyung Woo Choi; Dongsik Park; Won Jong Kim
Publication Date
2014-01
Journal
JOURNAL OF MATERIALS CHEMISTRY B, v.2, no.4, pp.341 - 356
Publisher
ROYAL SOC CHEMISTRYROYAL SOC CHEMISTRY
Abstract
Nitric oxide (NO) is one of the structurally smallest pharmaceutical molecules, which shows great potential as an anti-restenosis, wound healing, anticancer, and antibacterial agent. To date, while most of the studies have focused mainly on demonstrating the versatility of the NO-releasing materials, little effort has been made on developing successful NO-delivery strategies for advancing NO-mediated therapy. Thus, the quest for a rationally designed NO-delivery system is becoming one of the important issues in the biomedical applications of NO. This feature article discusses the overall research trends in the NOdelivery, focusing mainly on the various particle-type and coating platforms. The objective of this article is not only to highlight the fundamental principle and challenges associated with NO-delivery, but also to provide insight for the further development of novel NO-delivery platforms for clinical applications in the near future.
URI
https://pr.ibs.re.kr/handle/8788114/1153
ISSN
2050-750X
Appears in Collections:
Center for Self-assembly and Complexity(복잡계 자기조립 연구단) > Journal Papers (저널논문)
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