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A copper-mediated cross-coupling approach for the synthesis of 3-heteroaryl quinolone and related analogues

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Title
A copper-mediated cross-coupling approach for the synthesis of 3-heteroaryl quinolone and related analogues
Author(s)
Sanghye Shin; Yechan Kim; Kiho Kim; Sung Woo Hong
Publication Date
2014-08
Journal
ORGANIC & BIOMOLECULAR CHEMISTRY, v.12, no.30, pp.5719 - 5726
Publisher
ROYAL SOC CHEMISTRY
Abstract
An efficient and practical method for the direct cross-coupling between quinolones and a range of azoles was developed via copper-mediated C-H functionalization. This synthetic strategy provides a convenient access to a variety of C3-heteroaryl quinolones, quinolinone, nalidixic acid, uracil, pyridone and chromone derivatives, which are prominent structural motifs in many biologically active compounds.
URI
https://pr.ibs.re.kr/handle/8788114/960
DOI
10.1039/c4ob00939h
ISSN
1477-0520
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > 1. Journal Papers (저널논문)
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