BROWSE

Related Scientist

CNIR's photo.

CNIR
뇌과학 이미징 연구단
more info

ITEM VIEW & DOWNLOAD

Altered task-evoked corticolimbic responsivity in generalized anxiety disorder

Cited 0 time in webofscience Cited 0 time in scopus
12 Viewed 0 Downloaded
Title
Altered task-evoked corticolimbic responsivity in generalized anxiety disorder
Author(s)
Nayoung Kim; M. Justin Kim
Publication Date
2021-04
Journal
International Journal of Molecular Sciences, v.22, no.7, pp.1 - 11
Publisher
MDPI AG
Abstract
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.Generalized anxiety disorder (GAD) is marked by uncontrollable, persistent worry and exaggerated response to uncertainty. Here, we review and summarize the findings from the GAD literature that employs functional neuroimaging methods. In particular, the present review focuses on task-based blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) studies. We find that select brain regions often regarded as a part of a corticolimbic circuit (e.g., amygdala, anterior cingulate cortex, prefrontal cortex) are consistently targeted for a priori hypothesis-driven analyses, which, in turn, shows varying degrees of abnormal BOLD responsivity in GAD. Data-driven whole-brain analyses show the insula and the hippocampus, among other regions, to be affected by GAD, depending on the task used in each individual study. Overall, while the heterogeneity of the tasks and sample size limits the generalizability of the findings thus far, some promising convergence can be observed in the form of the altered BOLD responsivity of the corticolimbic circuitry in GAD.
URI
https://pr.ibs.re.kr/handle/8788114/9524
DOI
10.3390/ijms22073630
ISSN
1661-6596
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse