BROWSE

Related Scientist

cnir's photo.

cnir
뇌과학이미징연구단
more info

ITEM VIEW & DOWNLOAD

An equal-TE ultrafast 3D gradient-echo imaging method with high tolerance to magnetic susceptibility artifacts: Application to BOLD functional MRI

DC Field Value Language
dc.contributor.authorJae-Kyun Ryu-
dc.contributor.authorWon Beom Jung-
dc.contributor.authorJaeyong Yu-
dc.contributor.authorJeong Pyo Son-
dc.contributor.authorSeung-Kyun Lee-
dc.contributor.authorSeong-Gi Kim-
dc.contributor.authorJang-Yeon Park-
dc.date.accessioned2021-01-21T00:50:04Z-
dc.date.accessioned2021-01-21T00:50:04Z-
dc.date.available2021-01-21T00:50:04Z-
dc.date.available2021-01-21T00:50:04Z-
dc.date.created2020-11-16-
dc.date.issued2021-04-
dc.identifier.issn0740-3194-
dc.identifier.urihttps://pr.ibs.re.kr/handle/8788114/9077-
dc.description.abstractTo develop an ultrafast 3D gradient echo–based MRI method with constant TE and high tolerance to B0 inhomogeneity, dubbed ERASE (equal-TE rapid acquisition with sequential excitation), and to introduce its use in BOLD functional MRI (fMRI). Theory and Methods: Essential features of ERASE, including spin behavior, were characterized, and a comparison study was conducted with conventional EPI. To demonstrate high tolerance to B0 inhomogeneity, in vivo imaging of the mouse brain with a fiber-optic implant was performed at 9.4 T, and human brain imaging (including the orbitofrontal cortex) was performed at 3 T and 7 T. To evaluate the performance of ERASE in BOLD-fMRI, the characteristics of SNR and temporal SNR were analyzed for in vivo rat brains at 9.4 T in comparison with multislice gradient-echo EPI. Percent signal changes and t-scores are also presented. Results: For both mouse brain and human brain imaging, ERASE exhibited a high tolerance to magnetic susceptibility artifacts, showing much lower distortion and signal dropout, especially in the regions involving large magnetic susceptibility effects. For BOLD-fMRI, ERASE provided higher temporal SNR and t-scores than EPI, but exhibited similar percent signal changes inin vivo rat brains at 9.4 T. Conclusion: When compared with conventional EPI, ERASE is much less sensitive, not only to EPI-related artifacts such as Nyquist ghosting, but also to B0 inhomogeneity including magnetic susceptibility effects. It is promising for use in BOLD-fMRI, providing higher temporal SNR and t-scores with constant TE when compared with EPI, although further optimization is needed for human fMRI.-
dc.language영어-
dc.publisherJohn Wiley & Sons Inc.-
dc.titleAn equal-TE ultrafast 3D gradient-echo imaging method with high tolerance to magnetic susceptibility artifacts: Application to BOLD functional MRI-
dc.typeArticle-
dc.type.rimsART-
dc.identifier.wosid000583618700001-
dc.identifier.scopusid2-s2.0-85093953323-
dc.identifier.rimsid73604-
dc.contributor.affiliatedAuthorJae-Kyun Ryu-
dc.contributor.affiliatedAuthorWon Beom Jung-
dc.contributor.affiliatedAuthorJeong Pyo Son-
dc.contributor.affiliatedAuthorSeung-Kyun Lee-
dc.contributor.affiliatedAuthorSeong-Gi Kim-
dc.contributor.affiliatedAuthorJang-Yeon Park-
dc.identifier.doi10.1002/mrm.28564-
dc.identifier.bibliographicCitationMagnetic Resonance in Medicine, v.85, no.4, pp.1986 - 2000-
dc.relation.isPartOfMagnetic Resonance in Medicine-
dc.citation.titleMagnetic Resonance in Medicine-
dc.citation.volume85-
dc.citation.number4-
dc.citation.startPage1986-
dc.citation.endPage2000-
dc.description.journalClass1-
dc.description.journalClass1-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryRadiology, Nuclear Medicine & Medical Imaging-
dc.subject.keywordAuthorconstant echo time-
dc.subject.keywordAuthorecho-planar imaging-
dc.subject.keywordAuthormagnetic susceptibility artifacts-
dc.subject.keywordAuthorquadratic-phase encoding-
dc.subject.keywordAuthorspatiotemporal encoding-
dc.subject.keywordAuthorultrafast imaging-
Appears in Collections:
Center for Neuroscience Imaging Research (뇌과학 이미징 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse