BROWSE

Related Scientist

CCHF's photo.

CCHF
분자활성 촉매반응 연구단
more info

ITEM VIEW & DOWNLOAD

NHC-Catalyzed 1,2-Selective Hydroboration of Quinolines

Cited 0 time in webofscience Cited 0 time in scopus
9 Viewed 0 Downloaded
Title
NHC-Catalyzed 1,2-Selective Hydroboration of Quinolines
Author(s)
Jinseong Jeong; Joon Heo; Dongwook Kim; Sukbok Chang
Subject
1,2-regioselectivity, ; associative pathway, ; NHC catalysis, ; partial reduction, ; quinolines
Publication Date
2020-05
Journal
ACS CATALYSIS, v.10, no.9, pp.5023 - 5029
Publisher
AMER CHEMICAL SOC
Abstract
© 2020 American Chemical Society.Selective dearomative transformation of readily available N-heteroarenes is a powerful tool accessing useful synthetic building units. Described herein is the NHC-catalyzed 1,2-selective hydroboration of quinolines with high functional group tolerance. Dihydroquinoline products could be isolated as their amide derivatives upon in situ N-protection, thus offering high synthetic utility of the current procedure. Combined experimental and computational studies revealed that the observed regioselectivity can be rationalized by proposing a six-membered transition state that collectively incorporates NHC catalyst, hydroborane reductant, and protonated quinoline substrate
URI
https://pr.ibs.re.kr/handle/8788114/8618
DOI
10.1021/acscatal.0c00884
ISSN
2155-5435
Appears in Collections:
Center for Catalytic Hydrocarbon Functionalizations(분자활성 촉매반응 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
There are no files associated with this item.

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse