BROWSE

Related Scientist

lee,seunghwan's photo.

lee,seunghwan
유전체교정연구단
more info

ITEM VIEW & DOWNLOAD

Structural and dynamic views of the CRISPR-Cas system at the single-molecule level

Cited 3 time in webofscience Cited 4 time in scopus
699 Viewed 157 Downloaded
Title
Structural and dynamic views of the CRISPR-Cas system at the single-molecule level
Author(s)
Seung Hwan Lee; Bae S.
Subject
CRISPR-Cas system, ; Crystal structure, ; Single molecule, ; Type I CRISPR, ; Type II CRISPR
Publication Date
2016-04
Journal
BMB REPORTS, v.49, no.4, pp.201 - 207
Publisher
KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY
Abstract
The CRISPR-Cas system has emerged as a fascinating and important genome editing tool. It is now widely used in biology, biotechnology, and biomedical research in both academic and industrial settings. To improve the specificity and efficiency of Cas nucleases and to extend the applications of these systems for other areas of research, an understanding of their precise working mechanisms is crucial. In this review, we summarize current studies on the molecular structures and dynamic functions of type I and type II Cas nucleases, with a focus on target DNA searching and cleavage processes as revealed by single-molecule observations. © 2016 by the The Korean Society for Biochemistry and Molecular Biology
URI
https://pr.ibs.re.kr/handle/8788114/5807
DOI
10.5483/BMBRep.2016.49.4.042
ISSN
1976-6696
Appears in Collections:
Center for Genome Engineering(유전체 교정 연구단) > 1. Journal Papers (저널논문)
Files in This Item:
X사사_배상수_BMBreport.pdfDownload

qrcode

  • facebook

    twitter

  • Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse